Results 41 to 50 of about 977,117 (291)

Subcutaneous entomophthoromycoses

open access: yesIndian Dermatology Online Journal, 2015
Subcutaneous entomophthoromycoses is a zygomycosis caused by Basidiobolus ranarum that is endemic in southern India. We report the case of a 63-year-old male from central India who presented with a nontender subcutaneous hyperpigmented plaque on his leg with mild discharge that yielded Basidiobolus ranarum.
Tadepalli Karuna   +3 more
openaire   +3 more sources

Offspring subcutaneous adipose markers are sensitive to the timing of maternal gestational weight gain [PDF]

open access: yes, 2015
peer-reviewedBackground Excessive maternal weight gain during pregnancy impacts on offspring health. This study focused on the timing of maternal gestational weight gain, using a porcine model with mothers of normal pre-pregnancy weight.
Berry, Donagh   +7 more
core   +1 more source

Subcutaneous phaeohyphomycosis: A rare case

open access: yesDermatology Reports, 2019
Phaeohyphomycosis is a rare fungal infection caused by melanized fungi which usually involve the skin and subcutaneous tissue. It is an infrequent cause of infection in human beings. Common clinical manifestations are subcutaneous cystic swellings, which
Zahruddin Ahmad   +6 more
doaj   +1 more source

Subcutaneous Phycomycosis in a Child [PDF]

open access: yes, 2009
Subcutaneous phycomycosis is a rare entity. We hereby report a case of subcutaneous phycomycosis in 18 months old female child who presented with a painless, non-tender swelling on the thigh.
Jagtap, SV   +3 more
core  

A percutaneous needle biopsy technique for sampling the supraclavicular brown adipose tissue depot of humans. [PDF]

open access: yes, 2015
Brown adipose tissue (BAT) has been proposed as a potential target tissue against obesity and its related metabolic complications. Although the molecular and functional characteristics of BAT have been intensively studied in rodents, only a few studies ...
Annamalai, P   +6 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Injectables and Depots to Prolong Drug Action of Proteins and Peptides

open access: yesPharmaceutics, 2020
Proteins and peptides have emerged in recent years to treat a wide range of multifaceted diseases such as cancer, diabetes and inflammation. The emergence of polypeptides has yielded advancements in the fields of biopharmaceutical production and ...
Nkiruka Ibeanu   +7 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Diverse Mechanisms of Allergen Specific Immunotherapy

open access: yesRUDN Journal of Medicine, 2019
Allergen immunotherapy (AIT) is widely used to establish a tolerant immune response and it is currently the only disease modifying treatment. There are different routes to administer the allergen, including subcutaneous, sublingual, intralymphatic ...
Lacin Cevhertas, Mübeccel Akdis
doaj   +1 more source

Identifying a predictive relationship between maximal flow rate and viscosity for subcutaneous administration of macromolecules with recombinant human hyaluronidase PH20 in a miniature pig model

open access: yesDrug Delivery, 2023
Subcutaneous (SC) infusion of large volumes at rapid flow rates has historically been limited by the glycosaminoglycan hyaluronan (HA), which forms a barrier to bulk fluid flow in the SC space. Recombinant human hyaluronidase PH20 (rHuPH20) depolymerizes
Robert J. Connor   +2 more
doaj   +1 more source

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