Results 141 to 150 of about 511,586 (301)

Integrating Orbitofrontal Cortex into Prefrontal Theory: Common Processing Themes across Species and Subdivisions [PDF]

, 2001
Geoffrey Schoenbaum, Barry Setlow
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Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

The application of the Compulsory Subdivision, Building or Utilization of Land (CSBU)

, 2018
Rosana Denaldi, Dânia Brajato, Claudia Virginia Cabral de Souza, Henrique Botelho Frota   +3 more
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A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source

Probabilistic model-based functional parcellation reveals a robust, fine-grained subdivision of the striatum

, 2015
Ronald J. Janssen, Pasi Jylänki, Roy P. C. Kessels, Marcel van Gerven   +3 more
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Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

Stratigraphy and physical property of the Alluvium under the Tokyo and Nakagawa Lowlands, Kanto Plain, central Japan: implications for the Alluvium subdivision

, 2010
Susumu Tanabe, Yoshiro Ishihara, Toshimichi Nakanishi   +2 more
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Management Point Cloud Data based on GeoSOT-3D Subdivision Model

, 2021
Zhongyue Liu, Xian Guo
openalex   +1 more source

Designing Ductile 2‐GPa Yielding Titanium Alloys via Multifunctional Subgrain Boundaries and Nanoprecipitates

Advanced Science, EarlyView.
By engineering ultrafine β‐subgrains and nanoscale α‐precipitates in titanium alloys, the unique architecture achieves an unprecedented ultra‐high strength of 2 GPa while maintaining a notable uniform elongation of 6%, a combination that is both rare and highly promising for structural applications of titanium alloys.
Dingxuan Zhao, Kai Zu, Xu Yue, Hang Zhang, Zexuan Li, Keer Li, Zehua Zheng, Jialuo Yang, Wei Chen, Jinyu Zhang, Jun Sun   +10 more
wiley   +1 more source