Results 31 to 40 of about 1,227,291 (283)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Migration and workforce aging [PDF]

open access: yes, 2013
This chapter reviews recent research on migration and workforce aging, and examines the relationship between policy and practice in this contested area.
Field, John
core  

Modeling the evolution of natural cliffs subject to weathering. 2, Discrete element approach [PDF]

open access: yes, 2011
The evolution of slopes subjected to weathering has been modeled by assuming Mohr-Coulomb behavior and by using a numerical approach based on the discrete element method (DEM).
G. B. Crosta   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

SuDaField: Subject- and Dataset-Aware Neural Field for HRTF Modeling

open access: yesIEEE Open Journal of Signal Processing
This paper presents SuDaField, a subject- and dataset-aware neural field (NF) that can leverage multiple head-related transfer function (HRTF) datasets.
Yoshiki Masuyama   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Some problems in the design and analysis of field experiments subject to interplot interference

open access: yes, 2002
Results from field experiments with mobile pests and air-borne pathogens are subject to bias as a result of inter-plot interference. Serially balanced designs (SBDs) allow interference to be estimated but other designs may be better for decreasing such ...
Todd, A. D., Dyke, G. V., Jenkyn, J. F.
core   +1 more source

Profile of Student Algebraic Thinking with Polya's Problem-Solving Strategy: Study on Male Students with Field Independent Cognitive Style

open access: yesJTAM (Jurnal Teori dan Aplikasi Matematika), 2022
This study aims to describe the profile of students' algebraic thinking with Polya's problem solving strategy in completing a linear program conducted on male students with field independent cognitive style.
Nur Hardiani
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Teaching out-of-field in Western Australia

open access: yes, 2009
A former head of the American Federation of Teachers, Albert Shanker, once called out-of-field teaching education's "dirty little secret" (Ingersoll, 2003, p. 5).
Price, A.   +3 more
core   +1 more source

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