ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
ABOUT THE SUBJECT OF THE SERVICE CONTRACT ON PROVIDING INFORMATION
В статье раскрыты особенности предмета договора об оказании услуг по предоставлению информации. На основе проведенного анализа автором предлагается широкое значение предмета договора об оказании услуг по предоставлению информации, а также обозначены ...
Борисова Елена Сергеевна
core
Offer in government contracts [PDF]
Government in serving and perform their duties compelled of consolation contract, in this contract simple all of them, the public Accuracy is necessity.
ایمان دهقانی دهج +2 more
doaj +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
The loan contract with costly state verification and subjective beliefs [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar +3 more
wiley +1 more source
THE CONTRACT OF LEASE UNDER THE SERBIAN CIVIL CODE
Subject of this analysis is a contract of lease under the Serbian Civil Code (1844). The definition of the contract of lease encompasses two contracts: contract of service and contract of work.The contract of lease had been using also as anemployment ...
Gavrilović, Biljana
core +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Problems of application of a commercial concession agreement in the process of implementation of rights to intellectual property objects in business activities [PDF]
The article analyzes the actual problems of applying the commercial concession contract in the process of realizing rights to intellectual property objects in entrepreneurial activity.
Andrii Khridochkin +3 more
doaj +1 more source

