Results 201 to 210 of about 26,506 (286)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng   +4 more
wiley   +1 more source

Health and work: new times, new paradigms. [PDF]

open access: yesCad Saude Publica
Cordeiro R, Assunção AA.
europepmc   +1 more source

Machine Learning‐Based Estimation of Experimental Artifacts and Image Quality in Fluorescence Microscopy

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of image quality metrics in combination with machine learning enables automatic image quality assessment for fluorescence microscopy images. The method can be integrated into the experimental pipeline for optical microscopy and utilized to classify artifacts in experimental images and to build quality rankings with a reference‐free approach ...
Elena Corbetta, Thomas Bocklitz
wiley   +1 more source

IAR‐Net: Tabular Deep Learning Model for Interventionalist's Action Recognition

open access: yesAdvanced Intelligent Systems, EarlyView.
This study presents IAR‐Net, a deep‐learning framework for catheterization action recognition. To ensure optimality, this study quantifies interoperator similarities and differences using statistical tests, evaluates the distribution fidelity of synthetic data produced by six generative models, and benchmarks multiple deep‐learning models.
Toluwanimi Akinyemi   +7 more
wiley   +1 more source

Autonomous Recognition of Retained Secretions in Central‐Airway Based on Deep Learning for Adult Patients Receiving Invasive Mechanical Ventilation

open access: yesAdvanced Intelligent Systems, EarlyView.
This work presents a deep learning model to autonomously recognize and classify the secretion retention into three levels for patients receiving invasive mechanical ventilation, achieving 89.08% accuracy. This model can be implemented to ventilators by edge computing, whose feasibility is approved.
Shuai Wang   +6 more
wiley   +1 more source

Loss‐Based Ensemble Generative Adversarial Network Model for Enhancing the Sperm Morphology Classification

open access: yesAdvanced Intelligent Systems, EarlyView.
A loss‐based ensemble generative adversarial network (GAN) framework is proposed to address mode collapse in sperm morphology classification. By integrating spatial augmentation and multiple GAN models, the study enhances synthetic data quality. The Shifted Window Transformer achieves 95.37% accuracy on the HuSHeM dataset, outperforming previous ...
Berke Cansiz   +2 more
wiley   +1 more source

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