Advanced Science, EarlyView.Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen +6 more
wiley +1 more source
Reply: Rethinking sustained recompensation in MASLD cirrhosis: The value of pharmacological maintenance. [PDF]
Hepatol CommunJiménez-Masip A, Pulido JMP.
europepmc +1 more source
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Concerns Regarding the Design, Methodology, and Potential Biases in the Türkiye Heart Failure (TURK-HF) Registry. [PDF]
Clin CardiolZorlu Ç.
europepmc +1 more source
Improved Direct Ink Writing of Liquid Metal Foams via Liquid Additives
Advanced Electronic Materials, EarlyView.The ability to pattern liquid metal is useful for making soft electrical and thermal devices. Dispensing liquid metal from a nozzle naturally results in the formation of spheroidal droplets, making direct‐write printing challenging. Liquid metal foams containing pockets of air can extrude as filaments, albeit inconsistently.
Febby Krisnadi +3 more
wiley +1 more source
Measuring Nutrition Security Using the Consumer Food Data System Datasets
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Nutrition security is an emerging concept lacking a consensus definition, conceptualization, or standardized measure. This perspectives manuscript synthesizes findings from two previously published analyses to assess the feasibility of using available measures of key dimensions of nutrition security from two Consumer Food Data System (CFDS ...
Vibha Bhargava +2 more
wiley +1 more source
Subjectivity in paediatric urological imaging: a European Association of Urology-Young Academic Urologists (EAU-YAU) reliability study with consensus datasets. [PDF]
BJU IntKhondker A +13 more
europepmc +1 more source
Assessing Household Welfare in Response to Rising Food Prices in The Gambia
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT This study examines how rising food prices affected household welfare in The Gambia using nationally representative data from the 2015/16 Integrated Household Survey (IHS‐3). The analysis reflects household consumption behavior and market conditions prevailing during that period and provides a structural benchmark for understanding ...
Roger Vorsah +3 more
wiley +1 more source
Multimodal Sentiment and Emotion Analysis Framework for Personalized Health Coaching Messages: Proof-of-Concept Study. [PDF]
JMIR Form ResMd Zuki MA, Mohamad Ali N, Chaw JK.
europepmc +1 more source
How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang +4 more
wiley +1 more source