Results 31 to 40 of about 300,105 (310)

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Imaginaries of the ideal migrant worker : a Lacanian interpretation [PDF]

, 2014
The authors acknowledge the ESRC Centre for Population Change RES 62528001 for sponsoring this research.This paper explores the production of ‘ideal’ migrant workers by recruitment agencies in the context of Latvian labour migration to the UK.
Findlay, Allan MacKay, McCollum, David, Shubin, Sergei   +2 more
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Psychological Knowledge, Production of Subjectivity and Implications with the Bio-Politics

Interação em Psicologia, 2016
Este artigo discute a produção da psicologia como ciência nos parâmetros da racionalidade moderna e suas relações com a Biopolítica, sob a ótica do pensamento de Foucault, considerando que os discursos psicológicos operam como estratégias de controle, de
Ana Cristina Sundfeld
doaj   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Communication, desubjectivation and art

Visualidades, 2011
In this paper we try to reflect on the processes of subjectivity/desubjectivation in art using the notion of “device” as in Foucault: relationship established between individuals and the historical elements (institutions, procedures of subjectivity and ...
Nizia Maria Villaça
doaj   +1 more source

Marxist history and schooling: Beyond economism [PDF]

, 1994
Marxist history emphasises the linkage between economic production, social institutions and everyday life. Critics of Marxism claim that its analysis of schooling is simplistic, functional and deterministic The first part of this paper examines whether ...
Down, B.
core   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Processos interacionais e a construção de conhecimento e subjetividade de crianças Children's interactional processes and the production of knowledge and subjectivity

Psicologia: Reflexão e Crítica, 2004
Este artigo propõe uma discussão teórica acerca dos processos interacionais infantis concebidos como mediadores para a construção de conhecimento e subjetividade. Tem como pressuposto a compreensão da atividade discursiva como processo que integra ação e
Veriana de Fátima Rodrigues Colaço
doaj   +1 more source