Results 91 to 100 of about 4,138,522 (297)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

[Response Data: Improving Subjects in the Digital Collections with Data Survey]

, 2021
Complete, anonymized dataset of responses to the "Improving Subjects in the Digital Collections with Data" survey.
Miles, Chassidy, Tarver, Hannah, Zipperer, Rachael   +2 more
core  

Actividades de integración de conocimientos en el Grado de Farmacia. Aplicación en la asignatura de toxicología

Ars Pharmaceutica
Objetivos: Durante los últimos años, los profesores del Departamento de Farmacología, Toxicología y Química Terapéutica hemos puesto en marcha un conjunto de acciones docentes con el objetivo de promover en los alumnos del grado de Farmacia la mejora de ...
Miguel Rodamilans, Jesús Gómez-Catalán, Marta Barenys, Juan M. Llobet, David Pubill, Josefina Quirante   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Subjects of Nature

, 2012
info:eu-repo/semantics ...
Debaise, Didier
core  

Arterial stiffness evaluation in HIV-positive patients: a multicenter matched control study.

, 2011
: OBJECTIVE. The purpose of this article is to assess the differences, if any, in the values of carotid artery stiffness parameters between HIV-infected subjects without known cardiovascular disease (CVD) or carotid artery plaques and HIV-uninfected ...
Carlo Filice (217464), Giovanna Ferraioli, FILICE, CARLO, Scipione Carerj (11629902), FILICE, GAETANO, Pierfrancesco Grima, Giovanna Ferraioli (16176008), Martin Fisher (300134), Cristina Gervasoni, Gaetano Filice, Carlo Filice, Klaudija Viskovic (8594433), Grima P, Maggi P, Carerj S, Gaetano Filice (16176011), Paolo Maggi, Carmine Tinelli (25846), Paolo Maggi (4162249), Gervasoni C, Carmine Tinelli, Viskovic K, Klaudija Viskovic, Pierfrancesco Grima (4607479), and the Arterial Stiffness Evaluation in HIV-Infected Subjects S (16176014), FERRAIOLI, GIOVANNA, null null, Arterial Stiffness Evaluation in HIV Infected Subjects Study Group, Tinelli C, Scipione Carerj, Cristina Gervasoni (491743)   +30 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Obese subjects show sex-specific differences in right ventricular hypertrophy [PDF]

, 2014
As right ventricular (RV) remodeling in obesity remains underinvestigated, and the impact of left ventricular (LV) diastolic dysfunction on RV hypertrophy is unknown, we aimed to investigate whether (1) sex-specific patterns of RV remodeling exist in ...
Francis, JM, Rider, OJ, Lewandowski, AJ, Nethononda, R, Petersen, SE, Lewis, AJ, Neubauer, Stefan, Rider, Oliver, Ntusi, N, Leeson, Christopher, Lewi, AJM, Pitcher, A, Neubauer, S, Banerjee, R, Leeson, P   +14 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Temática dos artigos de periódicos brasileiros na área da ciência da informação na década de 90

Transinformação
Considerando-se a importância da comunicação científica para o progresso da ciência como forma de divulgar e patentear a pesquisa científica, analisa-se o periódico científico, impresso e eletrônico na área da Ciência da Informação.
Cláudia Maria Pinho de Abreu Pecegueiro
doaj