Results 101 to 110 of about 17,176 (269)

Artemisinin derivatives modulate KEAP1-NRF2-xCT pathway to alleviate Sjögren’s disease: insights from scRNA-seq and systems biology

Frontiers in Immunology
IntroductionSjögren’s Disease (SJD) is characterized by salivary gland dysfunction, and ferroptosis in salivary gland epithelial cells (SGECs) contributes to glandular damage.
Yong Luo, Liuting Zeng, Yanan Wang, Qianyue Yang, Chang Liu, Xiaojun Tang, Genhong Yao, Lingyun Sun, Lingyun Sun   +8 more
doaj   +1 more source

SOX2 regulates acinar cell development in the salivary gland [PDF]

, 2017
Acinar cells play an essential role in the secretory function of exocrine organs. Despite this requirement, how acinar cells are generated during organogenesis is unclear.
Andoniadou, Arnold, Aure, Boumahdi, Chou, Coughlin, Driskell, Goldsmith, Gontan, Herreros-Villanueva, Hoffman, Häärä, Jaskoll, Jiménez, Knosp, Knox, Knox, Lesko, Lizama, Lombaert, Lombaert, Lombaert, Ma, Matsumoto, Mattingly, Mead, Muench, Muzumdar, Nedvetsky, Nelson, Okubo, Pattyn, Pin, Que, Que, Smith, Steinberg, Suzuki, Tatsuta, Teshima, Ueno, Vasioukhin, Walker, Wanigasekara, Xiao, Zhao   +45 more
core   +1 more source

Investigating the Role of Ultrasound in the Diagnosis of Oral Lesions: A Scoping Review

Oral Diseases, EarlyView.
ABSTRACT Aim To provide an overview of the diagnostic potential of Ultrasound to assess oral lesions using Magnetic Resonance Imaging, Computed Tomography/Cone‐beam computed tomography, or histopathology as the reference standard. Methods A literature search was conducted from the following databases: OVID Medline and Embase, Web of Science, Pubmed ...
Camila Pacheco‐Pereira, Sheryn Villarey, Swarna Yerebairapura Math, Konrad Lehmann, Carlos Alberto Figueredo, Fabiana T. Almeida   +5 more
wiley   +1 more source

A morphometric study of human submandibular gland in type 2 diabetic status [PDF]

, 2013
Diabetes Mellitus Type 2 represents one of the principal diseases that afflict the world population. It is well documented that diabetes affects both morphology and function of several organs.
COSSU, MARGHERITA, ISOLA, MICHELA, LILLIU, MARIA ALBERTA, PUXEDDU, ROBERTO, SOLINAS, PAOLA   +4 more
core  

The Hippo signaling pathway is required for salivary gland development and its dysregulation is associated with Sjogren's-like disease [PDF]

, 2014
Sjogren's syndrome (SS) is a complex autoimmune disease that primarily affects salivary and lacrimal glands and is associated with high morbidity. Although the prevailing dogma is that immune system pathology drives SS, increasing evidence points to ...
Bouchie, Meghan, Enger, Tone Berge, Faustman, Denise L., Galtung, Hilde Kanli, Jensen, Janicke Liaaen, Kukuruzinska, Maria, Menko, A. Sue, Mera, Toshiyuki, Samad-Zadeh, Arman, Skarstein, Kathrine, Varelas, Xaralabos, Walker, Janice   +11 more
core   +1 more source

The Role of the Mylohyoid Line in the Spread of Mandibular Odontogenic Deep Neck Infection

Oral Diseases, EarlyView.
ABSTRACT Introduction Although mandibular odontogenic deep neck infections are occasionally fatal, the transmission pathway has not been elucidated. Materials and Methods This multicenter retrospective study was comprised of the patients of both sexes who were over 18 years of age and who had mandibular odontogenic deep neck abscesses.
Eiji Iwata, Kyoichi Obata, Shogo Kikuta, Naoki Kaneko, Kotaro Sato, Norio Kitagawa, Yohei Takeshita, Katsuhisa Matsuo, Junsei Sameshima, Akira Tachibana, Shintaro Kawano, Jingo Kusukawa, Masaya Akashi, Soichiro Ibaragi, Joe Iwanaga   +14 more
wiley   +1 more source

Sialolithiasis. Proposal for a new minimally invasive procedure: piezoelectric surgery [PDF]

, 2014
Sialolithiasis is the presence of stones in the ducts of the salivary glands. Most episodes are unique, and 60-80% are located exclusively in the main excretory duct.
Aracil Kessler, Luis, Cuervo Díaz, Alfonso, Pastor Ramos, Victoria   +2 more
core   +1 more source

Synergistic roles of aquaporin 5 and intra‐ and extracellular carbonic anhydrases in promoting CO2 diffusion across the Xenopus oocyte plasma membrane

The Journal of Physiology, EarlyView.
Abstract figure legend Fick's law: JCO2=PM*,CO2±hAQP5·([CO2]os±bCA−[CO2]is±hCAII)TransmembraneCO2gradient${J}_{{\mathrm{CO}}_{2}}=\underset{\pm \mathrm{hAQP}5}{\underset{}{{P}_{\mathrm{M}^\ast ,{\mathrm{CO}}_{2}}}}\, \cdot \underset{\mathrm{Transmembrane}\ {\mathrm{CO}}_{2}\ \mathrm{gradient}}{\underset{}{(\underset{\pm \mathrm{bCA}}{\underset ...
Deng‐Ke Wang, Fraser J. Moss, Walter F. Boron   +2 more
wiley   +1 more source

Role of M3 Muscarinic Acethylcholine Receptor Antibodies as a New Marker in Primary Sjögren Syndrome [PDF]

, 2017
Aims: This paper investigates the presence of M3 muscarinic acetylcholine receptor autoantibody present in the serum of patients with primary Sjögren syndrome (pSS).
Borda, Enri Santiago, Ganzinelli, Sabrina Belen, González Arana, Roberto, Pisoni, Cecilia, Reina, Silvia Lorena   +4 more
core   +1 more source

A feasibility study of functional preservation in craniospinal irradiation with photon for pediatric medulloblastoma

Journal of Applied Clinical Medical Physics, Volume 27, Issue 2, February 2026.
Abstract Background Craniospinal irradiation (CSI) is essential for treating pediatric medulloblastoma (MB) but causes significant long‐term toxicities. Existing dose‐reduction or partial‐sparing strategies improve neurocognitive outcomes but may compromise survival or fail to address other late effects.
Keqiang Wang, Jie Chen, Jianbo Jian, Peng Wang, Hongyang Zhang, Wenxue Zhang   +5 more
wiley   +1 more source