High-resolution density assessment assisted by deep learning of Dendrophyllia cornigera (Lamarck, 1816) and Phakellia ventilabrum (Linnaeus, 1767) in rocky circalittoral shelf of Bay of Biscay. [PDF]
Gayá-Vilar A +6 more
europepmc +1 more source
Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?
Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano +20 more
wiley +1 more source
Fiber-Optic Pressure Sensors: Recent Advances in Sensing Mechanisms, Fabrication Technologies, and Multidisciplinary Applications. [PDF]
Wang Y, Chen B, Wu G, Xue C, Gao L.
europepmc +1 more source
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani +4 more
wiley +1 more source
Analytical model of stress analysis for pipeline lowering-in during construction. [PDF]
Pang X +5 more
europepmc +1 more source
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham +8 more
wiley +1 more source
Shallow Hydrothermal Fluids Shape Microbial Dynamics at the Tagoro Submarine Volcano (Canary Islands, Spain). [PDF]
Pérez-Barrancos C +8 more
europepmc +1 more source
Prediction of the corrosion rates of subsea pipelines via KPCA. [PDF]
Xu S, Huang C, Zhao H.
europepmc +1 more source
A rapid DAS signal classification algorithm based on VMD and IMF power spectrum Gaussian fitting. [PDF]
Liu H, Xu Y, Qi Y, Bi W.
europepmc +1 more source
Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra +10 more
wiley +1 more source

