Results 221 to 230 of about 11,917 (312)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

open access: yesAdvanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham   +8 more
wiley   +1 more source

eDNAmap: A Metabarcoding Web Tool for Comparing Marine Biodiversity, With Special Reference to Teleost Fish. [PDF]

open access: yesMol Ecol Resour
Inoue J   +12 more
europepmc   +1 more source

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

open access: yesAngewandte Chemie International Edition, EarlyView.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra   +10 more
wiley   +1 more source

Safeguarding microbial biodiversity: microbial conservation specialist group within the species survival commission of the International Union for Conservation of Nature. [PDF]

open access: yesmSystems
Gilbert JA   +24 more
europepmc   +2 more sources

Study on Natural Gas Decarbonization Process Based on CO2 Desublimation Characteristics

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Natural gas decarbonization is a crucial processing step. In this study, the snow separation technology for removal of carbon dioxide in natural gas based on CO2 desublimation characteristics was introduced. The phase equilibrium calculation of CH4‐CO2 and N2‐CO2 system was carried out by using cubic equations of states (EOSs), and identified ...
Haiqin Wang   +3 more
wiley   +1 more source

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