Results 21 to 30 of about 9,596 (203)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Regional Models of Internal Tides [PDF]

open access: yes, 2012
Internal tides are ubiquitous in the ocean, and they play an important role in a range of ocean processes, for example, particle dispersal, acoustics, and vertical buoyancy flux. The wavelength of internal tides can be as much as 250 km in the open ocean,
Carter, Glenn S.   +2 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Scaling of a slope: the erosion of tilted landscapes [PDF]

open access: yes, 1998
We formulate a stochastic equation to model the erosion of a surface with fixed inclination. Because the inclination imposes a preferred direction for material transport, the problem is intrinsically anisotropic. At zeroth order, the anisotropy manifests
Pastor-Satorras, Romualdo   +1 more
core   +5 more sources

Cool Kitchen: Processing Starch and Eggshell Powder into Sustainable Coatings for Passive Daytime Cooling

open access: yesAdvanced Functional Materials, EarlyView.
A food‐grade cooling composite made from starch and recycled eggshell powder offers a scalable, ultra‐low‐cost solution for passive daytime radiative cooling. Easily prepared using basic kitchen tools, this material empowers communities, even in areas with limited infrastructure, to stay cooler during worsening summer heat waves.
Qimeng Song   +3 more
wiley   +1 more source

SMART Cables for Observing the Global Ocean: Science and Implementation [PDF]

open access: yes, 2019
The ocean is key to understanding societal threats including climate change, sea level rise, ocean warming, tsunamis, and earthquakes. Because the ocean is difficult and costly to monitor, we lack fundamental data needed to adequately model, understand ...
Arbic, Brian K.   +9 more
core   +1 more source

Carbon on the Northwest European Shelf: Contemporary Budget and Future Influences [PDF]

open access: yes, 2020
A carbon budget for the northwest European continental shelf seas (NWES) was synthesized using available estimates for coastal, pelagic and benthic carbon stocks and flows.
Aldridge, John   +30 more
core   +6 more sources

Scalable Polyelectrolyte Complex‐Based Sorbent With Hourly Sorption−Desorption Cycles for Multicyclic Atmospheric Water Harvesting in Arid Environments

open access: yesAdvanced Functional Materials, EarlyView.
A polyelectrolyte complex‐based sorbent is produced by scalable, environmentally benign aqueous phase inversion. Its porous, LiCl‐ and GO‐integrated architecture enables hourly adsorption−desorption cycles at low relative humidity (RH < 30%). A large‐scale prototype achieves multicyclic, solar‐driven atmospheric water harvesting of 1.37 L kg−1 day−1 ...
Seung‐Hwan Oh   +3 more
wiley   +1 more source

The Knowledge Application and Utilization Framework Applied to Defense COTS: A Research Synthesis for Outsourced Innovation [PDF]

open access: yes, 2019
Purpose -- Militaries of developing nations face increasing budget pressures, high operations tempo, a blitzing pace of technology, and adversaries that often meet or beat government capabilities using commercial off-the-shelf (COTS) technologies.
Gravier, Michael, Hawkins, Timothy
core   +1 more source

Home - About - Disclaimer - Privacy