Results 171 to 180 of about 1,126 (256)

Ongoing multiparameter unrest at the Montagne Pelée volcano on Martinique from 2019 to 2024. [PDF]

Sci Rep
Fontaine FR, Komorowski JC, Corbeau J, Burtin A, de Chabalier JB, Grandin R, Saurel JM, Agrinier P, Moune S, Jadelus F, Melezan D, Gabriel JG, Vidal C, Zimmermann B, Vaton D, Koziol J, Lavenaire JM, Moretti R, Lemarchand A, Labasque T, Blard PH, Tibari B, Zimmermann L, Aubaud C, Vergne J, Andrieu A, Filliaert A, Chilin-Eusebe E, Wahlgren SZ, Inostroza M, Métaxian JP, Potier A, Fernandez I, Robert V, Deroussi S, Carazzo G, Tait S, Vlastelic I, Jessop DE, Bonaimé S, Le Friant A, Chaussidon M, Michaud-Dubuy A, Retailleau L, Di Muro A, Allard P, Satriano C.   +46 more
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

A constellation of mud volcanoes originated from a buried Arctic mega-slide, Southwestern Barents Sea. [PDF]

Sci Rep
Argentino C, Mattingsdal R, Eidvin T, Ohm SE, Panieri G.   +4 more
europepmc   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Long-term deformation of coastal volcanoes in SE-Asia: linking displacement rates, volcanic activity and flank instabilities. [PDF]

Bull Volcanol
Zorn EU, Amelung F, Massimetti F, Laiolo M, Coppola D, Walter TR, Lavallée Y, Darmawan H.   +7 more
europepmc   +1 more source

The Impacts of Southwest Indian Ocean Tropical Cyclones on Transient Weather in Réunion

International Journal of Climatology, EarlyView.
Tropical cyclones which make passage near Réunion can have significant impacts on transient weather relative to long‐term means on the island. In this paper, these impacts were determined by a topological analysis of non‐landfalling tropical cyclones. The relationship between storm intensity, distance, duration, and seasonality plays an equal role in ...
Alexi M. Marinaki, Jennifer M. Fitchett
wiley   +1 more source

Unravel subseafloor hydrothermal leaching and magmatic degassing during chimney formation at Kolumbo volcano. [PDF]

Sci Rep
Hector S, Ahmad Q, Patten CGC, Chiaradia M, Nomikou P, Kilias S, Peillod A, Wagner S, Kolb J.   +8 more
europepmc   +1 more source

The German Soil Systematics and the Rationale Behind Its Revision

Journal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background The German Soil Systematics is a pedogenetic classification based on the morphological expressions of pedogenic processes and has been developed over several stages since 1952. The system has successfully been in use for soil classification and soil survey for almost 70 years.
Einar Eberhardt, Karl Stahr, Peter Schad, Alexander Gröngröft   +3 more
wiley   +1 more source