Results 211 to 220 of about 38,426 (298)

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

Annals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto, Michael Bonomo, Brianna S. Nelthrope, Benjamin D. Carr, Emma Palmer, Mariana Sierra, Ilkim Erturk, David Peppercorn, Eleonor Cox, Tiare K. Vasconcellos, Henry L. Paulson, Hannah K. Shorrock, Sharan R. Srinivasan   +12 more
wiley   +1 more source

3D Reconstruction of Mature <i>Arabidopsis</i> Ovules Using FIB-SEM to Study Filiform Apparatus Morphology. [PDF]

Bio Protoc
Oi T, Morikawa T, Yamazaki Y, Maruyama D, Susaki D.   +4 more
europepmc   +1 more source

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

Advanced NanoBiomed Research, EarlyView.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro, Aldo R. Boccaccini, Nicholas R. Forsyth, Tina P. Dale   +3 more
wiley   +1 more source

Combined electrospun fibre-microneedle patches for enhanced transmucosal delivery of benzodiazepines and proteins.

Biomater Sci
Berry C, Edmans JG, Slowik KM, Byers RA, Danby S, Hatton PV, Murdoch C, Colley HE.   +7 more
europepmc   +1 more source

Wormhole formation in fluid-driven granular flow. [PDF]

Commun Phys
Morgan ML, James DW, Monloubou M, Sandnes B.   +3 more
europepmc   +1 more source

Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction

Advanced NanoBiomed Research, EarlyView.
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen, Michael B. Nguyen, Elliot Widd, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Houston Harding, Chloe Hurteau, Anika Yogi, Colin Luo, Rebecca L. Braden, Pedro Cabrales, Karen L. Christman   +14 more
wiley   +1 more source

mRNA Delivery by Lipoamino Fatty Acid-Peptide Polyplexes in Different Lung Cell Models and Lungs. [PDF]

Polymers (Basel)
Thalmayr S, Müller J, Polewka V, Gialdini I, Nguyen A, Dohmen C, Lamb DC, Merkel OM, Wagner E.   +8 more
europepmc   +1 more source

4D Materials of Tough and Rapid Thermoresponsive Hydrogel by PET‐RAFT Polymerization

Journal of Applied Polymer Science, EarlyView.
NIPAm‐containing bilayer hydrogels using a novel hydrogel formation method utilizing oxygen‐tolerant PET‐RAFT polymerization to investigate their temperature‐responsive behavior. The material properties strongly depend on NIPAm concentration and polymer density. Finally, we demonstrated a model gripper with optimized compositions.
Chanhyuk Jee, Mina Shigeyama, Kakeru Ohbayashi, Ken Kojio, Hikaru Matsumoto, Masanori Nagao, Yoshiko Miura   +6 more
wiley   +1 more source

Extraction, Purification, and Characterization of Tannase Produced by <i>Aspergillus terreus</i> PQ344456 and Its Textile Dye Degradation and Juice Clarification Features. [PDF]

ACS Omega
Alhazmi NM.
europepmc   +1 more source

Expanded application to plant reproductive tissues of a branched DNA probe‐based in situ hybridization method

Applications in Plant Sciences, EarlyView.
Abstract Premise Detecting clear tissue‐ and organ‐specific patterns of gene expression is key to understanding the genetic mechanisms that control plant development. In situ hybridization (ISH) of mRNA is one of the most precise, yet most challenging approaches to gene expression assays.
Brooklyn M. Anaya, Austin T. Nguyen, Kelly K. S. Matsunaga, Lena C. Hileman   +3 more
wiley   +1 more source