Results 101 to 110 of about 315,319 (294)

Lanthanum Carbonate Nanosheets Based Colloidal Hydrogel for Modulating Innate & Adaptive Tumor Immunotherapy by Augmented Cellular Pyroptosis

open access: yesAdvanced Science, EarlyView.
The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong   +6 more
wiley   +1 more source

The Influence of the Design Features of the Submersible Pump Rotor on the Vibration Reliability

open access: yes
Pumping equipment consumes about 20 % of the electrical energy produced by humankind. A significant, even drastic, reduction in the weight and size indicators of pumping equipment leads to a decrease in the cost price and, therefore, competitiveness of ...
Makivskyi O.   +6 more
core   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu   +12 more
wiley   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Recip Pump on Unstable Condensate [PDF]

open access: yes, 2018
Case StudiesPump Design Conditions, Sealing/Packing System Design Features, Sealing/Packing System Failures, Pump Improvements, Conclusions and Lessons ...
Mascherpa, Luigi, Jakubiak, Jason
core   +2 more sources

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

open access: yesAdvanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva   +7 more
wiley   +1 more source

INTENSITY SETTER FOR A DEVICE OF SMOOTH START OF SUBMERSIBLE PUMP ELECTRIC MOTOR

open access: yesElectrical engineering & Electromechanics, 2016
Purpose. Development of an intensity setter, which in a rational law changes the opening thyristor the voltage regulator and effectively to changing power supply voltage stator windings of the electric pump deepening, ensuring a smooth start in a wide ...
V.I. Lobov, K.V. Lobova
doaj   +1 more source

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