Results 61 to 70 of about 245,390 (172)

Metastatic potential of small posterior uveal melanomas

open access: yesActa Ophthalmologica, Volume 104, Issue 2, Page e191-e203, March 2026.
Abstract Purpose To investigate the prevalence of aggressive traits in small posterior uveal melanomas (UM). Methods This retrospective, multicentre cohort study included 804 patients with small posterior UM (≤9 mm in largest basal diameter, ≤3 mm in thickness) from centres in the UK, Germany, and Sweden.
Gustav Stålhammar   +9 more
wiley   +1 more source

Comparison of Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging in Patients with Prostate Biopsy Indications

open access: yes, 2022
Objective: This article aims to evaluate the efficacy of multiparametric magnetic resonance imaging before standard tru-cut biopsy in making prostate cancer diagnosis.
Mehmet Sefa Altay   +15 more
core   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov   +8 more
wiley   +1 more source

Liquid biopsy from research to clinical practice : focus on non-small cell lung cancer

open access: yes, 2021
: Introduction In the current era of personalized medicine, liquid biopsy has acquired a relevant importance in patient management of advanced stage non-small cell lung cancer (NSCLC).
Pisapia, Pasquale   +20 more
core  

Biopsy confirmation of metastatic sites in breast cancer patients:clinical impact and future perspectives [PDF]

open access: yes, 2014
Determination of hormone receptor (estrogen receptor and progesterone receptor) and human epidermal growth factor receptor 2 status in the primary tumor is clinically relevant to define breast cancer subtypes, clinical outcome, and the choice of therapy.
Carmen Criscitiello   +38 more
core   +2 more sources

Clinico-pathologic correlation in ocular sarcoidosis

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: This case describes the unique course and management of a patient with progressive, refractory multi-system sarcoidosis that initially presented with ocular and dermatologic findings.
Arthi Rao   +6 more
doaj   +1 more source

A 51‐year‐old female presenting with headache and vision loss

open access: yes
Headache: The Journal of Head and Face Pain, Volume 66, Issue 8, Page 1928-1932, September 2026.
Laurel Ovrom   +3 more
wiley   +1 more source

Effects of Vemurafenib ± Cobimetinib on Intratumoral and Host Immunity in Patients With BRAFV600 Mutant Melanoma: Implications for Combination With Immunotherapy

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
We evaluated sequential tumor biopsies during therapy to test the hypotheses that BRAF/MEKi would increase TIL and lead to an expansion of functional intratumoral tumor‐reactive CD8 T‐cells and TIL clonality in the tumor microenvironment. Data from this study provides provocative evidence that, while BRAF+/−MEK inhibitor therapy produces an increase in
Suthee Rapisuwon   +12 more
wiley   +1 more source

Purtscher‐Like Retinopathy in a Young Male With Renal Failure Following Bodybuilding Supplement Overuse: A Case Report

open access: yesCase Reports in Medicine, Volume 2026, Issue 1, 2026.
Purtscher‐like retinopathy is a rare microvascular retinal disorder characterized by sudden visual loss and distinctive fundoscopic findings, often associated with systemic vascular insults. We report a 31‐year‐old male presenting with bilateral sudden blurred vision, hypertensive crisis, and renal failure following excessive intake of anabolic ...
Sahel Khazaei   +2 more
wiley   +1 more source

Syndromic Congenital Heart Disease Diagnosed in Adulthood: A Reminder of the Phenotypic Variability of Alagille Syndrome

open access: yesCase Reports in Cardiology, Volume 2026, Issue 1, 2026.
Alagille syndrome is a rare multisystemic genetic condition most commonly associated with neonatal liver disease. Variable expressivity is a defining feature of Alagille syndrome, resulting in a broad spectrum of phenotypic variation among individuals who meet the diagnostic criteria. We present an atypical case of cardiac‐predominant Alagille syndrome
Matthew K. Campbell   +4 more
wiley   +1 more source

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