Results 41 to 50 of about 2,157,323 (275)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Durable Protection in the European Union: The Case of Persons Fleeing Armed Conflicts
LawsUsing the case of persons fleeing armed conflicts, the present article examines the required pre-condition for local integration in the European Union (EU), namely the grant of durable protection.
Christel Querton, Iryna Hnasevych
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
, 2017 Magistrska naloga obravnava institut subsidiarne zaščite, ki je ena od oblik mednarodne zaščite v Evropski uniji. Subsidiarna zaščita je bila v pravo EU vpeljana na podlagi praks držav članic in predstavlja zaščito, ki dopolnjuje Konvencijo o statusu ...
Stare, Katja
core
Аналітично-порівняльне правознавствоThis article examines the institution of complementary protection in international refugee law through a comparative legal lens, focusing on three legal systems: the European Union’s subsidiary protection regime as codified in Regulation (EU) 2024/1347 (
O. V. Borovyk
doaj +1 more source
APPROACHES REGARDING THE SUSTAINABILITY AND ENVIRONMENTAL PROTECTION IN THE PHARMACEUTICAL INDUSTRY [PDF]
Fiabilitate şi Durabilitate, 2023 Sustainability and environmental protection are currently priorities of the pharmaceutical industry, a field in which more and more companies are interested in developing and implementing innovative technologies, finding sustainable solutions in the ...
Daniela CÎRŢÎNĂ
doaj
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Finanse i Prawo FinansoweThe purpose of the article. The article aims to reveal the existence of vacuum of norms regarding a group company in Indonesia, especially regarding the parent company's responsibility for bankruptcy experienced by its subsidiary. Methodology.
Annurdi +3 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source