Results 221 to 230 of about 32,682,305 (325)

Altered spectral patterns of aperiodic electroencephalography in autism

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim The altered ratio of neural excitation (E) and inhibition (I) has been proposed to the etiology of autism spectrum disorder (ASD). Previous studies suggested a lower E/I ratio in autistic individuals compared to non‐autistic comparisons (NACs) in specific brain regions.
Yi‐Ling Chien   +3 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier   +3 more
wiley   +1 more source

Unveiling sex dimorphism in the healthy cardiac anatomy: Fundamental differences between male and female heart shapes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We present a shape modelling‐based morphological analysis of sex differences in cardiac anatomy. We conduct our analysis on 456 healthy subjects from the UK Biobank (227M/229F) to uncover sex‐based differences in healthy cardiac morphology.
Beatrice Moscoloni   +4 more
wiley   +1 more source

Sound‐offset encoding is related to speech‐in‐noise perception at sentence level in older adults

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic summary of the study investigating sound‐onset and offset sensitivity in the brain of older adults. EEG responses to white‐noise bursts were recorded to examine neural encoding of sound onset and offset during passive listening and active task conditions.
Hasan Colak   +6 more
wiley   +1 more source

Applications of large‐scale artificial intelligence models in bioinformatics

open access: yesQuantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Large‐scale artificial intelligence (AI) models can mine potential patterns from massive amounts of data and provide more accurate analyses. This capability has enabled its gradual application in various areas of bioinformatics. However, few reviews have comprehensively summarized the applications of different types of large‐scale AI models in
Mingjing Li   +5 more
wiley   +1 more source

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