Results 111 to 120 of about 226,603 (334)

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Medication misuse and illicit substance use among palliative care patients in German palliative care units– an evaluation from the perspective of palliative care providers

Addiction Science & Clinical Practice
Background Palliative care focuses on controlling symptoms and improving the patient’s quality of life. To achieve this, medications with addictive potential are often used.
Jannis Eersink, Julian Maul, Nils Heuser, Astrid Morin, Martin Gschnell, Christian Volberg   +5 more
doaj   +1 more source

Victims’ experiences of the causes of substance misuse and its crime and parenting nexus in Nigeria: a qualitative study

Cogent Social Sciences
Substance misuse is a prevalent global problem. Yet, there remains a gap in using the fusion of social learning theory (SLT) and differential association theory (DAT) to examine victims’ experiences of the causes of substance use and its crime and ...
Tarela Juliet Ike, Chiyem Lucky Nwanzu, Kelvin Odeyovwi Ayobi, Mieyebi Lawrence Ike, Evangelyn Ebi Ayobi, Peremi Richmond Ike, Rukevwe Francis Doghor   +6 more
doaj   +1 more source

Tailored Organogel Systems for Optimized Pesticide Delivery: Mechanistic Insights and Agricultural Applications

Advanced Science, EarlyView.
Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang, SiYu Xv, Chao Wu, Nan Li, GuoPeng Teng, XuePing Huang, Jian Luo   +6 more
wiley   +1 more source

The Use of Cognitive Behavioural Therapy on Two Case Reports of Paraphilic Infantilism, Substance Misuse and Childhood Abuse [PDF]

, 2017
Samantha Banbury
openalex   +1 more source

Rapid and Direct Detection of Methamphetamine in Biofluids using a MXene‐Enabled Electrochemical Sensor

Advanced Science, EarlyView.
A MXene‐enhanced electrochemical sensor enables the rapid and direct detection of methamphetamine. Molecular simulations reveal that specific MXene surface functional groups act as key signal amplifiers by facilitating interfacial interactions. The sensor demonstrates high sensitivity and robust performance in complex biological matrices.
Ri Wang, Xiaofei Deng, Bo Chen, Jienan Shen, Wei Xu, Yingjie Zhu, Yi Zhang, Hui Yang   +7 more
wiley   +1 more source

Prevalence and associated factors in burnout and psychological morbidity among substance misuse professionals

BMC Health Services Research, 2008
Background Studies of psychological stress among substance misuse professionals rarely describe the nature of burnout and psychological morbidity. The main aim of this study was to determine the extent, pattern and predictors of psychological morbidity ...
Oyefeso Adenekan, Clancy Carmel, Farmer Roger   +2 more
doaj   +1 more source

Shedding Light on Common Misinterpretations in Photocatalyst Characterization

Advanced Energy Materials, EarlyView.
For heterogeneous semiconductor‐based photocatalysts, Marschall et al. highlight common misconceptions in material synthesis, characterization, and performance evaluation, together with detailed explanations on how to avoid them. The guidelines thus presented can help to improve reporting of photocatalyst performance in environmental applications, such
Roland Marschall, Lion Schumacher, Jennifer Strunk   +2 more
wiley   +1 more source

Misuse of medication in adult substance misuse services: a systematic review protocol [PDF]

, 2021
Rosalind Gittins, Louise Missen, Ian Maidment   +2 more
openalex   +1 more source

An Exploration of the Role of Substance Misuse Nurses in Scotland [PDF]

, 2004
Executive Summary Background With the increase of drug misuse over the past two decades, the role of the Substance Misuse Nurse has increased dramatically.
Bond, Christine M., Cameron, Isobel M., Cronkshaw, Grahame, Forest, John, Inkster, Karen, Lawrie, Thane, Matheson, Catriona I., van Teijlingen, Edwin, Wardell, Fiona A.   +8 more
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