Results 91 to 100 of about 373,515 (298)
Klinik Psikiyatri DergisiINTRODUCTION: It is known that adult ADHD comorbidity is high in cases with substance use disorder (SUD). With the prediction that the Behavioral Activation System (BAS) and the Behavioral Inhibition System (BIS), which Gray claims to underlie motivated ...
Esra Porgalı Zayman +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
European Journal of Investigation in Health, Psychology and EducationOffline forms of violence are evolving into their online counterparts. The aim of this study was to examine cyber child-to-parent violence by (1) analyzing its bidirectional relationships with offline CPV and distress, (2) identifying individual risk ...
Sara Rodriguez-Gonzalez +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
One-Year Retrospective Analysis of Adolescent Substance Use Treatment Clinic Cases
Sakarya Tıp DergisiObjective: This study aimed to examine the sociodemographic, clinical, psychosocial, and substance use characteristics of adolescents admitted to an outpatient Child and Adolescent Substance Addiction Treatment Center (ÇEMATEM) in Türkiye.
Enes Sarıgedik, Mustafa Tolga Tunagür
doaj +1 more source
Institutions and accounting standard transformation: Observations from Japan
China Journal of Accounting Research, 2014 This paper describes the transformation of Japan’s accounting standards over the past 2 decades and the driving forces behind this transformation.
Naohiro Urasaki
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Substance Over Form: A Principle for European Food Information Regulation?
, 2018 The question that is addressed in this chapter is whether food fraud can be mitigated using principles, next to or instead of rules. In many ways, principles may be preferred, as they reduce the regulatory burdens and avoid formal compliance while at the
Bremmers, Harry, Harry Bremmers
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source