Results 121 to 130 of about 373,515 (298)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The interaction between the substance over form doctrine and legislative anti-avoidance provisions

open access: yes, 2016
M.Com.Abstract: Tax avoidance is a burning issue in the tax environment and increasing attention has been drawn to it by the South African Revenue Service and the public.
Nicholls, Vanessa
core  

Executive function at baseline and follow-up in opioid maintenance patients and its relation to psychiatric comorbidity and substance use patterns

open access: yesBMC Psychiatry
Background Research investigating executive functions in opioid-dependent patients undergoing opioid maintenance treatment (OMT) is scarce. This study aimed to assess executive function in patients with opioid use disorder at treatment initiation and one-
John Hanson Högberg   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Substance-Over-Form Taxpayer and Foreign Investment Vehicle

open access: yes, 2019
이 글은 실질적 귀속자 개념이 조세조약의 해석적용에 어떤 영향을 주는가를 따 져본다. 실제는 두 가지 다른 논지를 담고 있다. 첫째는 2020년부터 시행되는 소득 세법 제119조의2와 법인세법 제93조의2(국외투자기구에 대한 실질귀속자 특례)의 글귀에 대한 매우 기술적인 법해석론이다.
이창희
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Form, Substance, and Section 1041

open access: yes, 1993
The article reviews recent cases and rulings dealing with the interplay of section 1041 with both (1) the assignment of income doctrine in the deferred compensation context and (2) the substance over form doctrine in the context of redemptions of closely
Geier, Deborah A
core  

Psychotropic substance use among medical residents: prevalence and characteristics

open access: yesEuropean Psychiatry
Introduction Psychotropic substance use among medical residents represents a critical concern due to its potential impact on patient care and practitioner well-being.
H. Ktari   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy