Decoding the Narratives: Analyzing Personal Drug Experiences Shared on Reddit [PDF]
arXivOnline communities such as drug-related subreddits serve as safe spaces for people who use drugs (PWUD), fostering discussions on substance use experiences, harm reduction, and addiction recovery. Users' shared narratives on these forums provide insights into the likelihood of developing a substance use disorder (SUD) and recovery potential.
arxiv
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
The self‐perceived survival ability and reproductive fitness (SPFit) theory of substance use disorders [PDF]
, 2002 David B. Newlin
openalex +1 more source
Fairness in Computational Innovations: Identifying Bias in Substance Use Treatment Length of Stay Prediction Models with Policy Implications [PDF]
arXivPredictive machine learning (ML) models are computational innovations that can enhance medical decision-making, including aiding in determining optimal timing for discharging patients. However, societal biases can be encoded into such models, raising concerns about inadvertently affecting health outcomes for disadvantaged groups.
arxiv
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEBS Open Bio, EarlyView.FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang +5 more
wiley +1 more source
Evidence-Based Treatments for Substance Use Disorders [PDF]
, 2003 Paul B. Gold, Kathleen T. Brady
openalex +1 more source
Post-Traumatic Stress Disorder and Substance Use Disorder Co-occurrence in Female Veterans [PDF]
, 2012 Female veterans often experience trauma, develop post-traumatic stress disorder (PTSD), and suffer from a substance use disorder (SUD). Females experience these disorders more than males and veterans experience them more than civilian populations.
Sholar, Jacqueline A.
core +1 more source
An Adaptive Control Approach to Treatment Selection for Substance Use Disorders [PDF]
arXivDespite the massive costs and widespread harms of substance use, most individuals with substance use disorders (SUDs) receive no treatment at all. Digital therapeutics platforms are an emerging low-cost and low-barrier means of extending treatment to those who need it.
arxiv
FEBS Open Bio, EarlyView.The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley +1 more source
An experimental evaluation of recovery management checkups (RMC) for people with chronic substance use disorders [PDF]
, 2003 Michael L. Dennis +2 more
openalex +1 more source