Results 31 to 40 of about 1,148 (137)

Collaborative reliance in medicine safety and quality regulation: Investigation of experiences in handling N-nitrosamine impurities among ZaZiBoNa participating countries

Frontiers in Medicine, 2022
IntroductionThe presence of N-nitrosamine impurities in medicines raised concerns globally as they are genotoxic and probable human carcinogens. A review of N-nitrosamine impurities in medicines provides an opportunity for National Regulatory Authorities
Patience P. Shabangu, Rutendo J. Kuwana, Admire Dube   +2 more
doaj   +1 more source

Artemisinin-Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control. [PDF]

Trop Med Int Health
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Mekasha YT, Tegegne AA, Mashe T, Girma M, Hasen G, Belew S.   +5 more
europepmc   +2 more sources

Medicine quality in high-income countries: The obstacles to comparative prevalence studies

Medicine Access @ Point of Care, 2021
The entry of falsified and substandard medicines into the legitimate pharmaceutical supply chain has negative impacts on healthcare systems, patient safety, and patient access to medicine. The COVID-19 pandemic has highlighted the importance of access to
Bernard David Naughton, Ebru Akgul
doaj   +1 more source

Review of drug recalls and quality of pharmaceutical products in Nepal

BMJ Open, 2022
Objectives To evaluate the pattern of substandard and falsified pharmaceutical products recall in Nepal.Setting We analysed drug recall notices issued by the Department of Drug Administration (DDA), Nepal, and systematically reviewed peer-reviewed ...
Astha Neupane, Maheshwor Bastakoti, Sabita Tamang, Basant Giri   +3 more
doaj   +1 more source

How to achieve international action on falsified and substandard medicines [PDF]

BMJ, 2012
Substandard and falsified medicines kill patients, yet progress on the twin challenges of safeguarding the quality of genuine medicine and criminalising falsified ones has been held back by controversy over intellectual property rights and confusion over terms.
Attaran, A, Barry, D, Basheer, S, Bate, R, Benton, D, Chauvin, J, Garrett, L, Kickbusch, I, Kohler, J, Midha, K, Newton, P, Nishtar, S, Orhii, P, McKee, M   +13 more
openaire   +4 more sources

A cross-sectional analysis of falsified, counterfeit and substandard medicines in a low-middle income country

BMC Public Health, 2020
Background High prevalence of falsified, counterfeit and substandard medicines pose a threat to public health and treatment failure. This study aimed to investigate the quality of selected essential medicines available in Mongolia.
Daariimaa Khurelbat, Gereltuya Dorj, Bruce Sunderland, Tsetsegmaa Sanjjav, Enkhtuul Bayarsaikhan, Davaadagva Damdinjav, Gantuya Dorj, Altantuya Jigjidsuren, Oyun Lkhagvasuren, Baasandorj Erdenetsetseg   +9 more
doaj   +1 more source

Importance of medicine quality in achieving universal health coverage.

PLoS ONE, 2020
ObjectiveTo assess the importance of ensuring medicine quality in order to achieve universal health coverage (UHC).MethodsWe developed a systems map connecting medicines quality assurance systems with UHC goals to illustrate the ensuing impact of quality-
Sachiko Ozawa, Colleen R Higgins, Tatenda T Yemeke, Jude I Nwokike, Lawrence Evans, Mustapha Hajjou, Victor S Pribluda   +6 more
doaj   +1 more source

Stemming the Global Trade in Falsified and Substandard Medicines

JAMA, 2013
WHEN HIPPOCRATES ADVISED PHYSICIANS TO never give a deadly drug, he assumed they would know for sure that the medicines they prescribed were safe. Today, criminals and unscrupulous manufacturers have permeated the global pharmaceutical market, calling into question this basic assumption of clinical practice.
Gostin, Lawrence O., Buckley, Gillian J., Kelley, Patrick W.   +2 more
openaire   +3 more sources

Substandard and falsified medicines

JMIR Public Health and Surveillance, 2021
The World Health Organization and others warn that substandard and falsified medicines harm health and waste money, especially in low- and middle-income countries. However, no country has measured the market-wide extent of the problem, and no standardized methods exist to estimate the prevalence of either substandard or falsified medicines. This is, in
Pisani, Elizabeth, Hasnida, Amalia, Rahmi, Mawaddati, Kok, Maarten Olivier, Harsono, Steven, Anggriani, Yusi   +5 more
openaire   +2 more sources

Discrimination of Falsified Erectile Dysfunction Medicines by Use of an Ultra-Compact Raman Scattering Spectrometer

Pharmacy, 2020
Substandard and falsified medicines are often reported worldwide. An accurate and rapid detection method for falsified medicines is needed to prevent human health hazards. Raman scattering spectroscopy has emerged as a non-destructive analysis method for
Tomoko Sanada, Naoko Yoshida, Kazuko Kimura, Hirohito Tsuboi   +3 more
doaj   +1 more source