Results 241 to 250 of about 1,614,980 (284)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Determining essential priorities for future investigation - A national consensus exercise in Interventional Oncology (DEFINE-IO) - An a priori protocol. [PDF]

PLoS One
Chan VW, Graham B, Ng HH, Griffiths S, Kotecha D, Ismail H, Jenkins P, Zhong J, Lakshminarayan R, Wah TM.   +9 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Trust, transparency, and disciplinary alignment in research funding evaluations: an illustrative case from the Norwegian AI Center call (2024-2025). [PDF]

Front Res Metr Anal
Krumsvik RJ, Johansen MO.
europepmc   +1 more source

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Rightist Parties and Women’s Substantive Representation

SSRN Electronic Journal, 2011
Conservative women are increasing their presence in politics – whether as elected representatives or organized as women’s groups in civil society- and women’s role in the public and private sphere is often a core theme of centre-right parties and policies. Nevertheless, rightist women and the role of centre-right parties are blind spots in the research
Celis, Karen, Childs, S
openaire   +2 more sources

On Substantive Representation, Diversity, and Responsiveness

Politics & Gender, 2012
When are “the people”—with all its different groups—represented? It is commonly accepted that democratic representation implies that no significant parts of the population are excluded from the right to vote or to stand for election and, similarly, that parliaments and even ...
openaire   +2 more sources

Descriptive and Substantive Representation of Poor Citizens in Switzerland

SSRN Electronic Journal, 2015
Over the past decade, a large number of studies have shown that in advanced democracies policymakers are more likely to represent the preferences of high-income citizens than the preferences of low-income citizens. In a quest to understand this income bias in substantive representation, several authors have recently suggested that the persistent ...
Lloren, Anouk, Rosset, Jan, Wuest, Reto
openaire   +3 more sources

Substantive Religious Representation in the U.S. Senate

Political Research Quarterly, 2008
Studies of representation are widespread in the congressional literature, with recent work focusing on both descriptive and substantive representation of various minority groups. The authors focus on religious representation in Congress, examining the extent to which senators’ own religious affiliation and the relative size of their religious ...
Lauren Edwards Smith, Laura R. Olson, Jeffrey A. Fine   +2 more
openaire   +1 more source

Women, Earmarks, and Substantive Representation

Journal of Women, Politics & Policy, 2013
The purpose of this article is to demonstrate women's substantive impact on government by examining the earmark requests of the US House representatives. Women representatives are hypothesized to make more funding requests for women's issues than male representatives.
openaire   +1 more source

The substantive representation of men: Intersectionality, masculinities, and men's interests [PDF]

European Journal of Political Research
Men’s numerical over-representation in politics leads to complacency regarding their substantive representation. Yet the men in politics are not descriptively representative of most men and are drawn disproportionately from the most socially privileged ...
Rainbow Murray
exaly   +2 more sources