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Substrates for Paraoxonase

Current Pharmaceutical Design, 2018
Background: Paraoxonase (PON) is a family of calcium-dependent hydrolases, which is related to many diseases. Elucidation of PON physiological roles, active center and all applications in medical fields are dependent on its substrates. Objective: The reports about PON substrates scattered in a long span of period are collected to afford clue for ...
Xiaojing, Mu   +5 more
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Interaction with Substrates

2020
Organometallic molecules have attracted interest because their properties can be varied by changing ligands, metal center, end groups etc. which makes them candidates for various applications. Special attention has been paid to hybrid systems of molecules and substrates as possible building blocks for future electronic and magnetic devices.
Herper, Heike C.   +6 more
openaire   +2 more sources

Substrate Channeling

Methods, 1999
Substrate channeling is the process in which the intermediate produced by one enzyme is transferred to the next enzyme without complete mixing with the bulk phase. This process is equivalent to a microcompartmentation of the intermediate, although classic diffusion occurs simultaneously to varying extents in many of these cases.
H O, Spivey, J, Ovádi
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Effects of substrate and substrate analogues on the trinitrophenylation of myosin

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1970
Abstract The effects of ATP, ATP analogues, Mg 2+ and actin on the trinitrophenylation of myosin and on the enzymic properties of trinitrophenylated samples were studied. 1. 1. Trinitrophenylation of myosin was inhibited by the presence of ATP and its analogues during the treatment in the order ADP > ATP > pyrophosphate > AMP. 2. 2.
A, Mühlrad, F, Fábián
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Lysozyme Substrates

1996
The natural substrate of lysozyme is the rigid layer of bacterial cell walls, the murein (peptidoglycan), which is a gigantic polymer of (GlcNAc-MurNAc)n polysaccharide strands crosslinked through short peptide bridges at the lactyl groups of the muramic acid residues.
openaire   +3 more sources

The Substrate Specificity of Sirtuins

Annual Review of Biochemistry, 2016
Sirtuins are NAD + -dependent enzymes universally present in all organisms, where they play central roles in regulating numerous biological processes.
Bheda, P.   +3 more
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cGK Substrates

2008
Signalling of cGK (cGMP-dependent protein kinases) are mediated through phosphorylation of specific substrates. Several substrates of cGKI and cGKII were identified meanwhile. Some cGKI substrates are specifically regulated by the cGKIalpha or the cGKIbeta isozyme.
Jens, Schlossmann, Matthias, Desch
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Substrate specificity of protein kinases and computational prediction of substrates

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005
To ensure signalling fidelity, kinases must act only on a defined subset of cellular targets. Appreciating the basis for this substrate specificity is essential for understanding the role of an individual protein kinase in a particular cellular process.
Kobe, Bostjan   +4 more
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Solidification on a substrate

Materials Science and Engineering, 1988
Abstract Most currently used rapid solidification techniques (such as melt spinning, melt extraction, melt drag, planar flow casting, double anvil, hammer and anvil and splat quenching) are simple variants on a common theme. Molten metal is brought into contact with a cool substrate, usually metallic. The molten metal forms a bond with the substrate,
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A substrate for telomerase

Trends in Biochemical Sciences, 2003
Recent data indicates that controlled in vivo synthesis of telomeric DNA is a 'ménage à trois', in which sister chromatid termini paired by telomere end-binding protein constitute a core substrate for a telomerase dimer. Such an arrangement could serve to fine tune synthesis of telomeric DNA and might ensure similar telomerase processivity for paired ...
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