Results 301 to 310 of about 2,477,868 (369)
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IEEE International Solid-State Circuits Conference, 2023
Recently, the demand for multi-chip solutions, such as chip-on-wafer-on-substrate (CoWoS) and embedded multi-die interconnect bridge (EMIB), is increasing as they reduce chip size and cost for high-performance computing (HPC), artificial intelligence (AI)
Kihwan Seong +15 more
semanticscholar +1 more source
Recently, the demand for multi-chip solutions, such as chip-on-wafer-on-substrate (CoWoS) and embedded multi-die interconnect bridge (EMIB), is increasing as they reduce chip size and cost for high-performance computing (HPC), artificial intelligence (AI)
Kihwan Seong +15 more
semanticscholar +1 more source
Engineering substrate specificity
Current Opinion in Structural Biology, 1991Site-directed mutagenesis of amino acids in the active site of an enzyme can yield mutant proteins with dramatically altered substrate specificity. In the past year, several enzymes have been successfully engineered with desired changes in specificity.
Charles Wilson, David A. Agard
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Substrate specificity of Streptomyces transglutaminases
Applied Biochemistry and Biotechnology, 2007Transglutaminase (TGase) is a multifunctional enzyme vital for many physiologic processes, such as cell differentiation, tissue regeneration, and plant pathogenicity. The acyl transfer function of the enzyme can activate primary amines and, consequently, attach them onto a peptidyl glutamine, a reaction important for various in vivo and in vitro ...
James, Langston +5 more
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Substrate specificity of neuraminidases
The Histochemical Journal, 1973This presentation is a brief description of neuraminidases and is mainly concerned with the substrate specificity of these enzymes. From the observed great differences in substrate specificity it is clear that we are dealing not with one enzyme called neuraminidase but with a variety of enzymes named neuraminidases.
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Substrate specificity of choline kinase
Archives of Biochemistry and Biophysics, 1987The substrate specificity of choline kinase (ATP:choline phosphotransferase, EC 2.7.1.32) from brewer's yeast has been examined using multiple analogs of choline, most of which have been reported to be a substrate of one or another choline-using system from other sources.
G L, Clary, C F, Tsai, R W, Guynn
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Substrate specificity of polyphenol oxidase
Critical Reviews in Biochemistry and Molecular Biology, 2020The ubiquitous type-3 copper enzyme polyphenol oxidase (PPO) has found itself the subject of profound inhibitor research due to its role in fruit and vegetable browning and mammalian pigmentation. The enzyme itself has also been applied in the fields of bioremediation, biocatalysis and biosensing.
Mark-Anthony, McLarin +1 more
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Substrate specificities of tobacco chitinases
The Plant Journal, 1998Ten tobacco chitinases (1,4-N-acetyl-beta-D-glucosaminide glycanhydrolase, EC 3.2.1.14) were purified from tobacco leaves hypersensitively reacting to tobacco mosaic virus. The 10 enzymes, which belong to five distinct structural classes of plant chitinases, were incubated with several potential substrates such as chitin, a beta-1,4 N-acetyl-D ...
F, Brunner +3 more
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Substrate specificity for pancreatic amylase
Gastroenterologia Japonica, 1978Substrates commonly used for the determination of amylase activity include potato starch, corn starch and dye-labeled starch. Determination of the amylase activity of serum using these different starches has shown that the measured value varies depending upon the ratio of isoamylases present, namely between pancreatic amylase (P-type) and salivary ...
T, Takeuchi +5 more
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Substrate specificity of squalene synthetase
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 198022 artificial homologues of farnesyl pyrophosphate were examined for the reactivity as substrate for squalene synthetase of pig liver microsomes. 16 of the homologues were found to be reactive to give corresponding squalene-like products. Extention of the omega-terminal of the carbon chain of farnesyl pyrophosphate is acceptable to the enzyme at least ...
T, Koyama, K, Ogura, S, Seto
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Journal of Biomedical Materials Research. Part A, 2020
Combat or burn injuries are associated with a series of risks, such as microbial infection, an elevated level of inflammatory response and pathologic scar tissue formation, which significantly postpone wound healing and also lead to impaired repair. Skin
Vajihe Taghdiri Nooshabadi +9 more
semanticscholar +1 more source
Combat or burn injuries are associated with a series of risks, such as microbial infection, an elevated level of inflammatory response and pathologic scar tissue formation, which significantly postpone wound healing and also lead to impaired repair. Skin
Vajihe Taghdiri Nooshabadi +9 more
semanticscholar +1 more source