Results 31 to 40 of about 861,541 (263)

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Modal Analysis and Structure Optimization of Permanent Magnet Synchronous Motor

IEEE Access, 2020
Permanent magnet synchronous motors are the core components of electric vehicles and widely used in the field of electric vehicles. The existence of vibration will reduce the operating efficiency and service life of the motor, which is the key factor to ...
Jian Zhao, Zhibin Wang, Haiqiang Liu, Fan Ning, Xuewu Hong, Jingjuan Du, Ming Yu   +6 more
doaj   +1 more source

Information Technology Business Value Measurement Framework [PDF]

پژوهش‌های مدیریت عمومی, 2018
This study aimed to develop a scientific framework to identify and measure the IT business value. Focus on finding a basis for determining the value of IT in business and to measure the performance of IT in the organization.
Kamran Feizi, Mohammad Taqi Taqavi Fard, Iman Raeisi Vanani, Mahdi Mahmoudsalehi   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The Stability Analysis of Rotor System Using Substructure Synthesis Method.

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C, 1998
Component Mode Synthesis method (CMS) is applied to the stability analysis evaluated by logarithmic decrement in order to reduce the calculating time. But usual CMS cannot be applied the rotor system that consists of bearings, seals and impellers, because inertia, stiffness and dammping matrices of the rotor system are umsymmetric matices.
IWATSUBO, Takuzo, KATSUMA, Toshifumi
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Quasicomparison Functions and Substructure Synthesis for Framed Structures Stability Analysis

Latin American Journal of Solids and Structures
The Rayleigh-Ritz-Meirovitch substructure synthesis method (RRMSSM) is extended to buckling analysis in framed structures. The objective is a computational procedure capable of yielding very accurate critical loads through solution of very-low-order ...
J. I. Colombo, C. A. Morales
doaj   +1 more source