Results 281 to 290 of about 40,678 (327)
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Connections of the subthalamic nucleus in the monkey
Brain Research, 1981Attempts were made to determine the afferent and efferent connections of the subthalamic nucleus (STN) in the monkey using retrograde and anterograde axoplasmic transport technics. Following HRP injections limited to the STN, label was transported to arrays of cells adjacent, and parallel, to the lateral medullary lamina in the rostral two thirds of ...
Patricia Conte +3 more
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The microcircuitry of primate subthalamic nucleus
Parkinsonism & Related Disorders, 2007Single-cell labeling experiments in cynomolgus monkeys have revealed that the subthalamic nucleus (STN) harbors several subtypes of projection neurons, each endowed with a highly patterned set of axon collaterals. This organizational feature allows single STN neurons to act directly upon the two major output structures of the basal ganglia--the ...
Martin Parent, André Parent
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Histogenesis of the subthalamic nucleus
Neuroscience, 1987Literature presents divergent hypotheses on the histogenesis of the subthalamic nucleus. The basal plate of the mesencephalon, the dorsal hypothalamus (or the longitudinal subthalamic zone) and an area closely related to the mammillary nucleus have all been proposed as the site of origin of the neurons of the subthalamic nucleus.
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GABAergic control of the subthalamic nucleus
2007The glutamatergic subthalamic nucleus (STN) is a key component of the basal ganglia, a group of subcortical brain nuclei important for voluntary movement and the site of dysfunction in Parkinson's disease. The rate and pattern of STN activity is precisely regulated by the reciprocally connected GABAergic external globus pallidus (GP(e)) and ...
Mark D. Bevan +2 more
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Subthalamic nucleus stimulation in Parkinson’s disease
Neurological Sciences, 2008Deep brain stimulation (DBS) is an effective surgical treatment for advanced Parkinson's disease (PD), with significant advantages in morbidity-mortality and quality of life when compared to lesion techniques such as thalamotomy and/or pallidotomy. The procedure is indicated in patients with severe resting tremor, unresponsive to conventional medical ...
Marconi, Roberto +2 more
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2015
Fue en 1865 cuando Jules Bernard Luys, un neurólogo francés, describió por primera vez una estructura gris de forma biconvexa, ubicada bilateralmente en la unión diencéfalo-mesencefálica y con una participación esencial en el control de los movimientos, a la que luego se le asignaron funciones adicionales en los procesos límbicos y cognitivos.
Fabián Piedimonte, Tania Acosta
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Fue en 1865 cuando Jules Bernard Luys, un neurólogo francés, describió por primera vez una estructura gris de forma biconvexa, ubicada bilateralmente en la unión diencéfalo-mesencefálica y con una participación esencial en el control de los movimientos, a la que luego se le asignaron funciones adicionales en los procesos límbicos y cognitivos.
Fabián Piedimonte, Tania Acosta
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Models of the subthalamic nucleus
Medical Engineering & Physics, 2004A coherent set of models is presented that provide novel and testable predictions about the functional role of the subthalamic nucleus (STN) in the basal ganglia. The STN is emerging as an important target for novel therapeutic strategies for the alleviation of Parkinsonian type symptoms [Lancet 345 (1995) 91; Science 249 (1990) 1436].
David Willshaw, Andrew Gillies
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Neurophysiological Refinement of Subthalamic Nucleus Targeting
Neurosurgery, 2002ABSTRACT OBJECTIVE Advances in image-guided stereotactic surgery, microelectrode recording techniques, and stimulation technology have been the driving forces behind a resurgence in the use of functional neurosurgery for the treatment of movement disorders.
Alon Y. Mogilner +6 more
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Somatotopic Localization in Rhesus Subthalamic Nucleus
Archives of Neurology, 1962In 1947, Mettler and Whittier 1 were able to produce abnormal bodily movements in monkeys by placing lesions in the subthalamic nucleus. These movements, occurring for the most part in the limbs, closely resembled those seen in ballism (flinging movements) or, more broadly, chorea ("dancing" movements).
Fred A. Mettler, Gerald M. Stern
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The microanatomical environment of the subthalamic nucleus [PDF]
Journal of Neurosurgery, 2007 ✓High-frequency stimulation of the subthalamic nucleus (STN) is a widely performed method to treat advanced Parkinson disease. Due to the limitations of current imaging techniques, the 3D microanatomy of the STN and its surrounding structures in the mesencephalon are not well known.
Yasin Temel +7 more
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