Results 301 to 310 of about 508,545 (369)

Characterization of Brain Abnormalities in Lactational Neurodevelopmental Poly I:C Rat Model of Schizophrenia and Depression Using Machine‐Learning and Quantitative MRI

open access: yesJournal of Magnetic Resonance Imaging, Volume 61, Issue 5, Page 2281-2291, May 2025.
Background A recent neurodevelopmental rat model, utilizing lactational exposure to polyriboinosinic‐polyribocytidilic acid (Poly I:C) leads to mimics of behavioral phenotypes resembling schizophrenia‐like symptoms in male offspring and depression‐like symptoms in female offspring. Purpose To identify mechanisms of neuronal abnormalities in lactational
Rona Haker   +10 more
wiley   +1 more source

Deep Brain Stimulation in Parkinson's Disease Patients Over 75 Years of Age: A Single‐Institution Retrospective Analysis

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 5, May 2025.
DBS is effective for alleviating motor symptoms in PD patients of advanced age (aged ≥ 75 years). Patients with a longer disease duration (≥ 10 years), regardless of the disease onset time, rarely reduce their use of antiparkinsonian drugs and improve their quality of life, and suffer relatively more short‐term complications.
Xin Wang   +13 more
wiley   +1 more source

Pallidal Deep Brain Stimulation Enhances Habitual Behavior in a Neuro‐Computational Basal Ganglia Model During a Reward Reversal Learning Task

open access: yesEuropean Journal of Neuroscience, Volume 61, Issue 9, May 2025.
Using our neuro‐computational model of the basal ganglia, we replicated the behavioral data of dystonia patients in a reversal‐learning task under DBS ON and OFF conditions. Our model suggests that DBS in the globus pallidus internus can diminish the basal ganglia's influence on decision‐making, thereby strengthening cortico‐thalamic connections and ...
Oliver Maith, Dave Apenburg, Fred Hamker
wiley   +1 more source

Unilateral Magnetic Resonance-Guided Focused Ultrasound Lesion of the Subthalamic Nucleus in Parkinson's Disease: A Prospective Study. [PDF]

open access: yesMov Disord
Armengou-Garcia L   +9 more
europepmc   +1 more source

Dual‐Site Beta tACS Over the rIFG and preSMA‐Induced Phase‐Specific Changes in Functional Connectivity but not Response Inhibition Performance in Older Adults

open access: yesPsychophysiology, Volume 62, Issue 5, May 2025.
ABSTRACT Research suggests that changes in functional connectivity contribute to age‐related declines in response inhibition. Through a double‐blind crossover study, we investigated the effects of dual‐site beta transcranial alternating current stimulation (tACS) over the right inferior frontal gyrus (rIFG) and pre‐supplementary motor area (preSMA) on ...
Jane Tan   +5 more
wiley   +1 more source

Subthalamic nucleus input-output dynamics are correlated with Parkinson's burden and treatment efficacy. [PDF]

open access: yesNPJ Parkinsons Dis
Liu X   +10 more
europepmc   +1 more source

Cognitive aspects of motor control deteriorate while off treatment following subthalamic nucleus deep brain stimulation surgery in Parkinson's disease. [PDF]

open access: yesFront Neurol
Munoz MJ   +10 more
europepmc   +1 more source

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