Results 171 to 180 of about 100,071 (296)

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

open access: yesInterdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li   +24 more
wiley   +1 more source

Effect of Zinc Oxide Nanoparticles From Infant Formula Milk Powder on Colon Cells In Vitro

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Zinc is an essential trace element that participates in numerous metabolic processes; however, excessive exposure may interfere with the absorption of other metals, such as copper. In recent years, nanotechnology has experienced rapid growth, and zinc oxide nanoparticles (ZnO NPs) have garnered significant attention due to their versatile ...
Gloria Salinas‐Lucero   +2 more
wiley   +1 more source

Differences in patterns of attention deficit/hyperactivity disorder medication use in US children

open access: yesJCPP Advances, EarlyView.
Abstract Background Understanding attention deficit/hyperactivity disorder (ADHD) medication patterns is crucial for optimizing treatment outcomes. There are limited data on racial, ethnic, gender and socioeconomic treatment differences across longitudinal national samples.
Jennie E. Ryan   +4 more
wiley   +1 more source

Neurodevelopmental variations cascading from age 10 months to 3 years leading to attention‐deficit hyperactivity disorder/autism traits at age 9 in a general population

open access: yesJCPP Advances, EarlyView.
Associations of neurodevelopmental measures (Z‐scores of gross motor, visual reception, fine motor, receptive language, expressive language) at ages 10, 14, 18, 24, 32, and 40 months with (a) attention‐deficit/hyperactivity disorder trait, (b) autism spectrum disorder trait, (c) developmental coordination disorder trait, and (d) intellectual ...
Kenji J. Tsuchiya   +14 more
wiley   +1 more source

Exploratory characterization of gut microbiota and cognitive profiles in adolescents with subthreshold depression: a shotgun metagenomics sequencing study. [PDF]

open access: yesNpj Ment Health Res
Wang R   +18 more
europepmc   +1 more source

Cyclothymic‐hypersensitive temperament in early adolescence: Longitudinal measurement invariance and associations with psychopathology over time

open access: yesJCPP Advances, EarlyView.
Abstract Background Cyclothymic‐Hypersensitive Temperament (CHT) is characterised by mood instability, interpersonal hypersensitivity, and emotional hyperreactivity, traits frequently observed in general population as well as clinical settings but often eluding strict diagnostic classifications.
Anna Pezzella   +9 more
wiley   +1 more source

Subthreshold Schottky-barrier transistor based on monolayer molybdenum disulfide. [PDF]

open access: yesNat Commun
Liu M   +13 more
europepmc   +1 more source

Normative scores and clinical cut‐offs of the Cyclothymic–Hypersensitive Temperament Questionnaire in adolescence

open access: yesJCPP Advances, EarlyView.
Abstract Background The Cyclothymic–Hypersensitive Temperament (CHT) is a multidimensional, transdiagnostic affective disposition characterized by mood instability, interpersonal sensitivity, heightened emotional reactivity and impulsive behaviors. The CHT Questionnaire (CHTQ) currently lacks of normative references and empirically derived thresholds ...
Anna Pezzella   +10 more
wiley   +1 more source

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