Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli +4 more
wiley +1 more source
Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos +3 more
wiley +1 more source
Exploratory characterization of gut microbiota and cognitive profiles in adolescents with subthreshold depression: a shotgun metagenomics sequencing study. [PDF]
Wang R +18 more
europepmc +1 more source
Normobaric hyperoxia enhances antioxidant defenses and promotes tissue repair, improving functional outcomes. However, its perioperative application in lung cancer patients remains limited. Normobaric hyperoxia combined with perioperative pulmonary rehabilitation may reduce postoperative LOS and total hospitalization cost for VATS‐treated patients ...
Mei Zhou +14 more
wiley +1 more source
Efficacy of Traditional Chinese Medicine psychosomatic integration therapy for subthreshold depression: a multicenter randomized controlled trial. [PDF]
Wenyue HU +6 more
europepmc +1 more source
Understanding subthreshold depression.
openaire +3 more sources
Estimating Cognitive Impairment in Bipolar Disorder: Should We Account for Premorbid IQ?
ABSTRACT Introduction Cognitive impairment estimations traditionally rely on the deviation of current cognitive performance from population norms (normative approach). Since bipolar disorder (BD) has been associated with above‐average premorbid cognitive functioning in some studies, this approach might underestimate the extent of cognitive impairment ...
Dimosthenis Tsapekos +5 more
wiley +1 more source
Brain-predicted age difference is associated with the progression of subthreshold depression: evidence from the UK Biobank. [PDF]
Dai H +10 more
europepmc +1 more source
In a longitudinal cohort of individuals with alcohol use disorder (AUD), spontaneous remission after one year was associated with lower baseline AUD severity, lower levels of alcohol intake, and fewer drinking days. Machine learning showed moderate prediction of persistent AUD, with AUDIT score as the strongest predictor. Baseline characteristics serve
Judith Zaiser +18 more
wiley +1 more source
Identifying Physiological and Cognitive Indicators of Subthreshold Depression and Major Depressive Disorder Progression Risk. [PDF]
Shimizu A +10 more
europepmc +1 more source

