Results 81 to 90 of about 36,790 (248)

Stress Promotes Drug Seeking Through Glucocorticoid-Dependent Endocannabinoid Mobilization in the Prelimbic Cortex [PDF]

, 2018
Background Clinical reports suggest that rather than directly driving cocaine use, stress may create a biological context within which other triggers for drug use become more potent. We hypothesize that stress-induced increases in corticosterone “set the
Baker, David A., Cravatt, Benjamin F., Doncheck, Elizabeth M., Graf, Evan N., Hillard, Cecilia J., Li, Yan, Liu, Qing-Song, Mantsch, John R., McReynolds, Jayme R., Ogasawara, Daisuke, Vranjkovic, Oliver   +10 more
core   +1 more source

Associations of familial risk factors with social fears and social phobia: evidence for the continuum hypothesis in social anxiety disorder? [PDF]

, 2009
We examined parental psychopathology and family environment in subthreshold and DSM-IV threshold conditions of social anxiety disorder (SAD) in a representative cohort sample of 1,395 adolescents. Offspring and parental psychopathology was assessed using
Susanne Knappe, Katja Beesdo, Lydia Fehm, Roselind Lieb, Hans-Ulrich Wittchen, CA Alfano, NC Andreasen, WA Arrindell, B Bandelow, K Beesdo, SM Bögels, MJ Chartier, PN Christensen, PJ Cooper, EJ Costello, RM Crum, JRT Davidson, HL Egger, L Fehm, L Fehm, AJ Fyer, EA Heerey, JM Hettema, JL Hudson, N Ialongo, JG Johnson, RI Kabacoff, K Keenan, MB Keller, KS Kendler, RC Kessler, RC Kessler, G Lachner, JP Lépine, R Lieb, R Lieb, WJ Magee, EB McClure, KR Merikangas, JM Milne, C Perris, V Reed, AM Ruscio, J Schumacher, MB Stein, MB Stein, RL Spitzer, CT Taylor, S Taylor, SM Turner, MJ Voncken, JC Wakefield, JK Wilson, HU Wittchen, HU Wittchen, HU Wittchen, HU Wittchen, J Woodruff-Borden, W Zhang   +58 more
core   +3 more sources

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

Advanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen, Cong Minh Nguyen, Quang Thang Trinh, Minh Anh Huynh, Khanh Vinh Ho, Dang Co Pham, Dzung Dao, Sven Ingebrandt, Sina Jamali, Xuan Thang Vu, Nam‐Trung Nguyen, Tuan‐Khoa Nguyen   +11 more
wiley   +1 more source

Always on my mind: Cross-brain associations of mental health symptoms during simultaneous parent-child scanning. [PDF]

, 2019
How parents manifest symptoms of anxiety or depression may affect how children learn to modulate their own distress, thereby influencing the children's risk for developing an anxiety or mood disorder.
Antonacci, Chase, Aupperle, Robin L, Bodurka, Jerzy, Burrows, Kaiping, Cosgrove, Kelly T, DeVille, Danielle C, Kerr, Kara L, Misaki, Masaya, Moore, Andrew J, Morris, Amanda Sheffield, Ratliff, Erin L, Silk, Jennifer S, Simmons, W Kyle, Tapert, Susan F   +13 more
core  

Interferon-γ acutely augments inhibition of neocortical layer 5 pyramidal neurons [PDF]

, 2020
BACKGROUND: Interferon-γ (IFN-γ, a type II IFN) is present in the central nervous system (CNS) under various conditions. Evidence is emerging that, in addition to its immunological role, IFN-γ modulates neuronal morphology, function, and development in ...
Bräuer, Anja U., Byvaltcev, Egor, Döhne, Noah, Grosser, Sabine, Janach, Gabriel M. S., Reetz, Olivia, Stadler, Konstantin, Strauss, Ulf   +7 more
core   +1 more source

Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output

Advanced Science, EarlyView.
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin, Shulan Xiao, Krishna Jayant   +2 more
wiley   +1 more source

A Randomized Depression Prevention Trial Comparing Interpersonal Psychotherapy—Adolescent Skills Training To Group Counseling In Schools [PDF]

, 2016
Given the rise in depression disorders in adolescence, it is important to develop and study depression prevention programs for this age group. The current study examined the efficacy of Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST), a ...
Benas, J. S., Gallop, R., Gillham, Jane, Mufson, L., Schueler, C. M., Young, J. F.   +5 more
core   +1 more source

Alexithymia and cognitive behaviour therapy outcome for subthreshold depression [PDF]

Acta Psychiatrica Scandinavica, 2008
Objective:  Alexithymia is hypothesized to be a stable trait that hinders favourable outcomes of psychotherapy. We tested two hypotheses: i) alexithymia is not stable but changes along with a change in depressive symptoms and ii) pretreatment alexithymia hinders gaining benefits from psychotherapy.Method:  A total of 201 participants (mean age = 54 ...
Spek, V., Nyklicek, I., Cuijpers, P., Pop, V.   +3 more
openaire   +3 more sources

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Transcranial Electric Stimulation Entrains Cortical Neuronal Populations in Rats [PDF]

, 2010
Low intensity electric fields have been suggested to affect the ongoing neuronal activity in vitro and in human studies. However, the physiological mechanism of how weak electrical fields affect and interact with intact brain activity is not well ...
Anastassiou, Costas A., Belluscio, Mariano A., Buzsáki, György, Koch, Christof, Ozen, Simal, Sirota, Anton, Stark, Eran   +6 more
core   +1 more source