Results 31 to 40 of about 4,870 (242)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

A missed opportunity: how signal detection theory can advance research on prejudice detection

open access: yesFrontiers in Organizational Psychology
Subtle, everyday prejudice continues to affect outcomes in work, education, counseling, and health care. A critical step toward mitigating these effects is the ability to recognize prejudice when it occurs, yet individuals often disagree about whether a ...
Stephanie M. Merritt
doaj   +1 more source

Leaky Pipeline Myths: In Search of Gender Effects on the Job Market and Early Career Publishing in Philosophy

open access: yesFrontiers in Psychology, 2017
That philosophy is an outlier in the humanities when it comes to the underrepresentation of women has been the occasion for much discussion about possible effects of subtle forms of prejudice, including implicit bias and stereotype threat.
Sean Allen-Hermanson
doaj   +1 more source

Do urban tourists prefer vegetarianism? An urban-rural comparison of vegetarian consumption in China

open access: yesFrontiers in Nutrition, 2022
The adoption of a vegetarian diet might have public health and environmental benefits. However, little is known about urban and rural Generation Z tourists' attitudes toward vegetarianism or vegetarian consumption within the Chinese urban and rural ...
Guoyi Chen   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Prejudice Transformation from Overt to Covert Forms as an Indicator of its Functions in Intergroup Relations

open access: yesСоциальная психология и общество
Objective. The study is aimed to clarify the understanding of the functions of prejudice in intergroup relations. A comparison of approaches to explaining intergroup relations and an analysis of the transformation of prejudice into covert ...
M.V. Kotova
doaj   +1 more source

Subtle Increases in BMI within a Healthy Weight Range Still Reduce Womens Employment Chances in the Service Sector. [PDF]

open access: yesPLoS ONE, 2016
Using mixed design analysis of variance (ANOVA), this paper investigates the effects of a subtle simulated increase in adiposity on women's employment chances in the service sector.
Dennis Nickson   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy