Results 11 to 20 of about 91,311 (188)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Quantum noise eater for a single photonic qubit
, 2013 We propose a quantum noise eater for a single qubit and experimentally verify its performance for recovery of a superposition carried by a dual-rail photonic qubit.
Dušek, Miloslav +3 more
core +1 more source
Realizing arbitrary-precision modular multiplication with a fixed-precision multiplier datapath [PDF]
, 2009 Within the context of cryptographic hardware, the term scalability refers to the ability to process operands of any size, regardless of the precision of the underlying data path or registers.
Grossschaedl, Johann +4 more
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Background field method in the large $N_f$ expansion of scalar QED
, 2019 Using the background field method, we, in the large $N_f$ approximation, calculate the beta function of scalar quantum electrodynamics at the first nontrivial order in $1/N_f$ by two different ways.
Deng, Gai-Ge, Zheng, Zhi-Yuan
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Arithmetic--some drill aspects [PDF]
, 1927 Thesis (M.A.)--Boston ...
Finneran, Elizabeth Margaret
core +1 more source
The nucleus of 103P/Hartley 2, target of the EPOXI mission
, 2010 103P/Hartley 2 was selected as the target comet for the Deep Impact extended mission, EPOXI, in October 2007. There have been no direct optical observations of the nucleus of this comet, as it has always been highly active when previously observed.
C. Snodgrass +14 more
core +1 more source
Surface Terms as Counterterms in the AdS/CFT Correspondence [PDF]
, 1999 We examine the recently proposed technique of adding boundary counterterms to the gravitational action for spacetimes which are locally asymptotic to anti-de Sitter.
A. Chamblin +49 more
core +3 more sources
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source