Results 41 to 50 of about 3,840,697 (280)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

A general algorithm to build mixed real and virtual antenna functions for higher-order calculations

Journal of High Energy Physics, 2023
The antenna-subtraction technique has demonstrated remarkable effectiveness in providing next-to-next-to-leading order in α s (NNLO) predictions for a wide range of processes relevant for the Large Hadron Collider.
Oscar Braun-White, Nigel Glover, Christian T. Preuss   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Digital Subtraction Radiography in the Evaluation of Early Alveolar Bone Density Changes Using Dried Mandible: An Original Radiological In Vitro Study

Journal of Indian Academy of Oral Medicine and Radiology
Background: Radiographic examination provides essential information for diagnosing periodontal disease and evaluating the results of periodontal treatment. The digital subtraction technique is a radiographic analysis method that can detect subtle changes
Dylan Dharmalaksana, Menik Priaminiarti, Bramma Kiswanjaya, Inka Saraswati, Hanna Bachtiar   +4 more
doaj   +1 more source

Subtraction Procedures of Salivary Gland Scintigrams in Mice [PDF]

, 1985
P(論文)In order to obtain clear salivary gland images, subtraction scintigraphy was attempted in the mouse neck. The purpose of this attempt was to eliminate the unwanted thyroid gland image which appeared overlapped with the salivary gland image.
21862, 金子, 昌幸, 35001, 大西, 隆, 35000, 菊池, 文利, 34998, 内海, 治, 34997, 小林, 光道, 高野, 英明, 35002, 34999, 金田, 英生   +13 more
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Development of a Voxel-Matching Technique for Substantial Reduction of Subtraction Artifacts in Temporal Subtraction Images Obtained from Thoracic MDCT [PDF]

, 2010
A temporal subtraction image, which is obtained by subtraction of a previous image from a current one, can be used for enhancing interval changes (such as formation of new lesions and changes in existing abnormalities) on medical images by removing most ...
石川, 聖二, 6285, 6284, 25, 金, 亨燮, 80295005, Katsuragawa, Shigehiko, 6281, 90128116, Itai, Yoshinori, Ishikawa, Seiji, 55739611300, 402, Doi, Kunio, 404, Kim, Hyoungseop, イシカワ, セイジ, 55539203500   +17 more
core   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Digital Subtraction Radiography - A Technique Revisited

Journal of Indian Academy of Oral Medicine and Radiology, 2007
Digital imaging has changed the scenario of medical and dental imaging as it has been able to address many limitations associated with traditional film based radiograph.
Anshul Mehra, Amar A Sholapurkar, Auswaf Ahsan, Keerthilatha M Pai   +3 more
doaj