Results 71 to 80 of about 9,914,485 (355)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Stand-Alone Rod Augmentation for Instrumentation Failure after Pedicle Subtraction Osteotomy: A Case Report with a 2-Year Follow-up

Journal of Orthopedic and Spine Trauma, 2021
Background: Revision surgery of spine can be a complex procedure and has known complications. It involves hardware revision, removal of scar/callus tissue, realignment of sagittal balance, and anterior augmentation.
Mohammad Zarei, Mohsen Rostami, Furqan Mohammed Yaseen Khan   +2 more
doaj   +1 more source

Video foreground detection based on symmetric alpha-stable mixture models. [PDF]

, 2010
Background subtraction (BS) is an efficient technique for detecting moving objects in video sequences. A simple BS process involves building a model of the background and extracting regions of the foreground (moving objects) with the assumptions that the
Achim, A., Bhaskar, H., Mihaylova, Lyudmila   +2 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Performance Analysis of the New Flexible Double Weight (FDW) Code With Various Detection Techniques

IEEE Access
In this paper, Spectral Amplitude Coding Optical Code Division Multiple Access (SAC-OCDMA) system performance is analyzed using a Flexible Double Weight (FDW) code with various detection techniques. In theoretical analysis, various types of noise such as
Muhammad Amirul Anuar, Syed Mohammad Ammar, Rosdisham Bin Endut, Syed Alwee Aljunid Syed Junid, Norshamsuri Ali, Mohamad Naufal Saad, Hamza Mohammed Ridha Al-Khafaji   +6 more
doaj   +1 more source

Fingerprint Spectrophotometric Methods for the Determination of Co-Formulated Otic Solution of Ciprofloxacin and Fluocinolone Acetonide in Their Challengeable Ratio

Journal of Analytical Methods in Chemistry, 2019
Six spectrophotometric methods were developed to determine a new single-dose otic solution known as “Otovel®,” which consists of two components: the major one is ciprofloxacin (CIP) and the minor is fluocinolone acetonide (FLU).
Reem H. Obaydo, Amir Alhaj Sakur
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Pedicle Subtraction Osteotomy in Treatment of Posttraumatic Kyphosis

Egyptian Spine Journal, 2017
Background Data: One of the worst complications of spine fracture is posttraumatic kyphosis, and beside pain and disability, new neurological deficit may develop and need surgical interference, that is challenging.
Ahmed Arab, Mohamed Elmaghrabi, Mohamed Eltantawy   +2 more
doaj   +1 more source

Image Subtraction Reduction of Open Clusters M35 & NGC 2158 In The K2 Campaign-0 Super-Stamp

, 2017
Observations were made of the open clusters M35 and NGC 2158 during the initial K2 campaign (C0). Reducing these data to high-precision photometric time-series is challenging due to the wide point spread function (PSF) and the blending of stellar light ...
Bakos, G. A., Bhatti, W., Hartman, J. D., Huang, C. X., Penev, K., Soares-Furtado, M.   +5 more
core   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source