Results 291 to 300 of about 1,747,151 (350)

Recombinant subunit vaccines

Current Opinion in Biotechnology, 1991
Research that may lead to the development of recombinant DNA-based vaccines has been conducted on a broad front. This has resulted in an increased understanding of immunological responsiveness to vaccines, the rational engineering of immunogens, and new means of delivering vaccines.
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Pulmonary Administration of Subunit Vaccines

2014
Pulmonary administration of vaccines might overcome some of the disadvantages related to administration by needle. The lungs are equipped with various immune cells through which a systemic as well as a mucosal immune response can be induced. Different types of devices and formulations can be used to administer vaccines to the lungs, each with their own
Tonnis, Wouter F., Huckriede, Anke L.W., Hinrichs, Wouter L.J., Frijlink, Henderik W.   +3 more
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The herpes zoster subunit vaccine

Expert Opinion on Biological Therapy, 2016
Herpes zoster (HZ) causes severe pain and rash in older people and may be complicated by prolonged pain (postherpetic neuralgia; PHN).HZ results from reactivation of latent varicella-zoster virus (VZV) infection, often associated with age related or other causes of decreased T cell immunity.
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Immersion vaccination of Mandarin fish Siniperca chuatsi against infectious spleen and kidney necrosis virus with a SWCNTs-based subunit vaccine.

Fish and Shellfish Immunology, 2019
Infectious spleen and kidney necrosis virus (ISKNV) cause a high mortality disease which lead to significant economic loss on mandarin fish in China. There is no effective drug or vaccine against this fatal disease at present.
Zhao Zhao, Chen Zhang, Yi-Jun Jia, De-Kui Qiu, Q. Lin, Ningqiu Li, Zhi-Bin Huang, Xiao-Zhe Fu, Gao-Xue Wang, Bin Zhu   +9 more
semanticscholar   +1 more source

Temporal release of a three-component protein subunit vaccine from polymer multilayers.

Journal of Controlled Release, 2019
Sustained antigen and adjuvant availability have been shown to improve antiviral immune responses following vaccination. Transcutaneous delivery of vaccines using microneedles has also shown promise and may be particularly relevant for mosquito-borne ...
D. S. Uppu, M. Turvey, Abdul Rahim Mohamed Sharif, Katell Bidet, Yanpu He, Victor Ho, Anagha Tambe, J. Lescar, E. Tan, K. Fink, Jian-Zhu Chen, P. Hammond   +11 more
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Construction and analysis of the immune effect of Vibrio harveyi subunit vaccine and DNA vaccine encoding TssJ antigen.

Fish and Shellfish Immunology, 2019
Vibrio harveyi, a severe pathogen infects different kinds of sea animals, causes huge economic loss in aquaculture industry. In order to control the Vibriosis disease caused mainly by V. harveyi and other Vibrio spp., the best solution lies in developing
Yun Sun, Susu Ding, Mingwang He, A. Liu, H. Long, Wei-Liang Guo, Zhen-Jie Cao, Zhen-Yu Xie, Yong-can Zhou   +8 more
semanticscholar   +1 more source

Enhanced protective immunity to CSFV E2 subunit vaccine by using IFN-γ as immunoadjuvant in weaning piglets.

Vaccine, 2018
The glycoprotein E2 of classical swine fever virus (CSFV) is a major immunogenic protein that induces neutralizing antibodies and protective immunity.
Hua-Wei Zhang, Wei Wen, Ze-Kai Zhao, Jianjian Wang, Huan-Chun Chen, P. Qian, Xiang-Min Li   +6 more
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Enhanced protective immunity against spring viremia of carp virus infection can be induced by recombinant subunit vaccine conjugated to single-walled carbon nanotubes.

Vaccine, 2018
As a successful prevention strategy for controlling the highly contagious and pathogenic disease of spring viremia of carp (SVC), DNA vaccines reported in recent years could trigger protective responses against SVC with the means of injection.
Chen Zhang, Linhan Li, Jin Wang, Zhao Zhao, Jian Li, Xiao Tu, Ai-Guo Huang, Gao-Xue Wang, Bin Zhu   +8 more
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EFFECTIVE PROTECTION AGAINST INFLUENZA AFTER VACCINATION WITH SUBUNIT VACCINE

Medical Journal of Australia, 1978
Immunization with an influenza subunit vaccine given in one dose about 1 month to 2 months before onset of an epidemic of influenza afforded from 80% to 90% protection in a double-blind clinical trial which was supported by isolation of virus and serological studies. In the vaccinated group, 20% failed to develop antibodies to the vaccine.
M L, Hammond, A A, Ferris, S, Faine, T, McAvan   +3 more
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Adjuvanting a subunit COVID-19 vaccine to induce protective immunity

Nature, 2021
P. Arunachalam, A. Walls, Nadia A. Golden, C. Atyeo, S. Fischinger, Chunfeng Li, P. Aye, M. Navarro, Lilin Lai, V. Edara, K. Röltgen, K. Rogers, Lisa M. Shirreff, D. Ferrell, S. Wrenn, D. Pettie, J. C. Kraft, Marcos C. Miranda, Elizabeth Kepl, Claire Sydeman, Natalie Brunette, M. Murphy, B. Fiala, L. Carter, Alexander G. White, M. Trisal, C. Hsieh, Kasi E. Russell-Lodrigue, C. Monjure, Jason P. Dufour, Skye Spencer, L. Doyle-Meyers, R. Bohm, N. Maness, C. Roy, Jessica A. Plante, K. Plante, A. Zhu, M. Gorman, Sally A. Shin, Xiao-Ying Shen, Jane Fontenot, Shakti S. Gupta, D. O'Hagan, R. G. van der Most, R. Rappuoli, R. Coffman, David W. Novack, J. McLellan, S. Subramaniam, D. Montefiori, S. Boyd, J. Flynn, G. Alter, F. Villinger, H. Kleanthous, J. Rappaport, M. Suthar, N. King, D. Veesler, B. Pulendran   +60 more
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