Results 101 to 110 of about 18,535,059 (331)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The Role of Organizational Factors on Spin-Offs Success in Iran Defense Industries [PDF]

open access: yesبهبود مدیریت, 2015
Fulfillment of R&D core and network approach in a ministry that technology is one of the capitals and bases of its business, can be a challenging and complicated issue.
Qasem Fooladi   +1 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Smart Government Success Factors

open access: yesYearbook of Swiss Administrative Sciences, 2018
Smart information and communication technologies are finding their way into public administration. Today, there are numerous initiatives in the public sector, promising a new model for the public services: smart government.
A. Guenduez   +4 more
semanticscholar   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Critical success factors & risks in property investment in China [PDF]

open access: yes, 2001
This paper attempts to provide some insights toward critical success factors, risks encountered and suggestions by foreign investors in property investment in Xiamen (Special Economic Zone), China.
Adul Hamid, Razali, Lim, Soon Kam
core  

Critical success factors in early new product development: a review and a conceptual model

open access: yes, 2018
The literature on the front end in the New Product Development (NPD) literature is fragmented with respect to the identification and analysis of the factors that are critical to successful product development. The article has a two-fold purpose.
Henrik Florén   +3 more
semanticscholar   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Financial Metrics and Environment, Social, Governance (ESG) Performance: A Cross Border Comparison of China and the UK Construction Industries

open access: yesBuildings
Environmental, social, and governance (ESG) performance has become a pivotal factor for multinational corporations, especially within resource-intensive sectors like construction.
Hector Martin, Yuheng Zhou, Raghu Raman
doaj   +1 more source

Factors impacting knowledge transfer success in information systems outsourcing [PDF]

open access: yes, 2010
Despite increased research interest on knowledge transfer in information systems (IS) outsourcing, the field still lacks sound and holistic understanding of the key factors influencing knowledge transfer success.
Al-Salti, Z, Hackney, R, Ozkan, S
core  

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