Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Societal Impact Statement Novel forest ecosystems consist of forest ecosystems dominated by non‐native tree species that are difficult to restore to their pre‐human disturbance states.
Zu Dienle Tan +12 more
doaj +1 more source
Forest Stand Structure and Primary Production in relation to Ecosystem Development, Disturbance, and Canopy Composition [PDF]
Temperate forests are complex ecosystems that sequester carbon (C) in biomass. C storage is related to ecosystem-scale forest structure, changing over succession, disturbance, and with community composition.
Scheuermann, Cynthia M
core +1 more source
The Adequacy of the Presidential Succession System in the 21st Century: Filling the Gaps and Clarifying the Ambiguities in Constitutional and Extraconstitutional Arrangements [PDF]
Program for the Adequacy of the Presidential Succession System in the 21st Century: Filling the Gaps and Clarifying the Ambiguities in Constitutional and Extraconstitutional Arrangements.https://ir.lawnet.fordham.edu/twentyfifth_amendment_miscellaneous ...
Fordham Law Review, Fordham Law School
core +4 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Twenty-Fifth Amendment to the United States Constitution: A Reader\u27s Guide [PDF]
Historic overview and analysis of presidential succession coupled with findings of the law ...
Yale Law School Rule of Law Clinic
core +1 more source
The role of organisational culture during the implementation of internal succession planning within Malaysian research universities [PDF]
Succession planning is not new to academia and many institutions have supported these programs for years. Few, however, have adopted formal succession planning strategies that are both strategic and deliberate and encompass the full spectrum of ...
Keerio, Nazia
core
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Temporary ponds are habitats that undergo periods of drying and flooding. They have been neglected for many years and changes produced by climatic change will greatly affect them.
Amaia Pérez-Bilbao +2 more
doaj +1 more source

