Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The Effects of Different Substrates in Pond Net Cages on the Succession of Periphyton and the Seedling Protection of Sea Cucumber Apostichopus japonicus. [PDF]
Wu Y +6 more
europepmc +1 more source
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Differentiation of water sources and hydrological thresholds of herb-to-shrub communities across a revegetated chronosequence in Baijitan National Nature Reserve, China: a quantitative analysis using hydrogen-oxygen stable isotopes. [PDF]
Shunxia W +4 more
europepmc +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Microbial succession in human tissues postmortem: insights from 2bRAD-M sequencing. [PDF]
Huang X +8 more
europepmc +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Topological vulnerability explains fungal and bacterial stability differences in restoration of alpine grasslands. [PDF]
Zhao J, Lu Q, Zhang X, Dong S.
europepmc +1 more source

