Results 31 to 40 of about 367,825 (287)
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The Relevance of Law to Sovereign Debt [PDF]
, 2015 The literature on sovereign debt treats law as of marginal significance, largely because the doctrine of sovereign immunity leaves creditors few potent legal remedies against sovereign borrowers.
Gulati, Mitu, Weidemaier, W. Mark C.
core +3 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Testamentary Freedom and its Bounds in an International Succession Case
Teisė, 2019 This article presents the legal steps that should be made in an intercountry succession case dealing with testamentary succession – first of all, which court is competent to value the will; second, according to which law it should be done.
Simona Bronušienė
doaj +1 more source
, 2010 In view of the profound importance of questions of presidential succession and the lack of attention paid to them, this issue of the Fordham Law Review is, very simply, a great public service.
Treanor, William Michael
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Das Erbrecht in weltgeschichtlicher Entwickelung (1824–1835) von Eduard Gans [PDF]
Rechtsgeschichte - Legal History, 2007 Das Erbrecht in weltgeschichtlicher Entwickelung, although unquestionably the most ambitious work of Eduard Gans, has hitherto been generally neglected by scholars.
Corrado Bertani
doaj +1 more source
Administration of the Estate under Regulation (EU) No. 650/2012
Review of European and Comparative Law, 2021 In the period between the deceased person’s death and division of assets in the deceased person’s estate among the heirs, an essential matter is administration of the estate.
Jacek Górecki
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source