Results 161 to 170 of about 6,481 (185)

Sucrase‐isomaltase Gene Variants in Patients With Abnormal Sucrase Activity and Functional Gastrointestinal Disorders

Journal of Pediatric Gastroenterology and Nutrition, 2020
ABSTRACTObjectives:The aim of the study was to determine prevalence and characterize sucrase‐isomaltase (SI) gene variants of congenital sucrase‐isomaltase deficiency in non‐Hispanic white pediatric and young adult patients with functional gastrointestinal disorders (FGIDs), and abnormal sucrase activity on histologically normal duodenal biopsy.Methods:
Chirajyoti, Deb, Stephani, Campion, Veronica, Derrick, Vanessa, Ruiz, Bassam, Abomoelak, Angelina, Avdella, Baiming, Zou, Karoly, Horvath, Devendra I, Mehta   +8 more
openaire   +2 more sources

Tryptic Digestion of Native Small‐Intestinal Sucrase · Isomaltase Complex: Isolation of the Sucrase Subunit

European Journal of Biochemistry, 1975
Limited tryptic digestion of native sucrase · isomaltase complex produced a more rapid destruction of isomaltase activity than sucrase activity. It was possible to isolate a partially fragmented sucrase subunit in high yields with a specific activity twice that of the native complex.
A, Quaroni, E, Gershon-Quaroni, G, Semenza   +2 more
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Dextran synthesis by immobilized dextran sucrase

Biochimie, 1980
Dextran sucrase has been produced by fermentation of Leuconostoc mesenteroides NRRL B-512, with and without continuous sucrose addition to improve enzyme production. The enzyme preparation has been concentrated from the fermentation broth by ultrafiltration and purified by gel permeation chromatography on Ultrogel.
A, Lopez, P, Monsan
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Evaluation of liquid yeast-derived sucrase enzyme replacement in patients with sucrase-isomaltase deficiency

Gastroenterology, 1993
No enzyme replacement therapy exists for patients with congenital sucrase-isomaltase deficiency (CSID). A by-product of the manufacture of baker's yeast is a liquid preparation containing high sucrase activity. The aim of the present study was to investigate the activity and stability of this preparation and its effect on breath hydrogen excretion and ...
W R, Treem, N, Ahsan, B, Sullivan, T, Rossi, R, Holmes, J, Fitzgerald, R, Proujansky, J, Hyams   +7 more
openaire   +2 more sources

Sacrosidase Therapy for Congenital Sucrase-Isomaltase Deficiency

Journal of Pediatric Gastroenterology & Nutrition, 1999
ABSTRACTBackground:The purpose of this study was to determine if sacrosidase, a liquid produced from Saccharomyces cerevisiae containing 6000 IU of sucrase activity per mg protein, prevented symptoms of diarrhea, abdominal cramps, gas, and bloating in patients with congenital sucrase‐isomaltase deficiency (CSID) consuming a normal sucrose and ...
W R, Treem, L, McAdams, L, Stanford, G, Kastoff, C, Justinich, J, Hyams   +5 more
openaire   +2 more sources

Congenital Sucrase-isomaltase deficiency:

1996
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Ouwendijk, J., Moolenaar, E.C., Peters, W.J.M, Hollenberg, C.P., Ginsel, L.A., Fransen, J.A.M.   +5 more
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Secretion of Sucrase by Leishmania donovani

Journal of Eukaryotic Microbiology, 1994
ABSTRACT. Leishmania donovani promastigotes were collected, washed, resuspended in buffer, and assayed for sucrase activity. No activity was observed in the intact washed cells, but activity was measurable when the cells were permeabilized with Triton X‐100.
J J, Blum, F R, Opperdoes
openaire   +2 more sources

Sucrase and cellular development.

Ciba Foundation symposium, 1980
The cellular changes that take place as the intestinal cell migrates from crypt to villus are morphologically and biochemically remarkable. It is fortunate that many of these phenomena can be delineated by following enzymic activities. Sucrase-isomaltase is a particularly fascinating enzyme complex because it is a marker of the differentiated cell ...
N, Kretchmer, J S, Latimer, F, Raul, K, Berry, C, Legum, H L, Sharp   +5 more
openaire   +1 more source

Intestinal peptidases and sucrase in coeliac disease

Clinica Chimica Acta, 1981
The activities of microvillus aminopeptidase (microsomal, EC 3.4.11.2), dipeptidyl peptidase IV (EC 3.4.14.-), glycyl-leucine dipeptidase (EC 3.4.13.11), proline dipeptidase (EC 3.4.13.9), sucrase (EC 3.2.1.48) and gamma-glutamyl transpeptidase (EC 2.3.2.2) were measured in peroral intestinal biopsies taken from patients with coeliac disease in the ...
H, Sjöström, O, Norén, P A, Krasilnikoff, E, Gudmand-Høyer   +3 more
openaire   +2 more sources

Congenital Sucrase-Isomaltase Deficiency

Journal of Pediatric Gastroenterology and Nutrition, 1995
openaire   +3 more sources