Results 51 to 60 of about 331,979 (290)

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

On Unsaturated Soil Mechanics – Personal Views on Current Research

Studia Geotechnica et Mechanica, 2015
This paper presents the authors’ personal views on current research being conducted by various research groups around the world in the broad area of mechanics of unsaturated geomaterials in general and soils in particular.
Pande G.N., Pietruszczak S.
doaj   +1 more source

Incidence of seroma in abdominoplasty with versus without the use of drains and quilting sutures: a systematic review and meta-analysis [PDF]

Revista Brasileira de Cirurgia Plástica, 2019
Introduction: Abdominoplasty, which aims to improve body contour, has been upgraded by its association with limited dissection of the cutaneous flap and quilting sutures in the same surgery to avoid the formation of postabdominoplasty seroma, a ...
Katrienne Guidolini Martinelli, Caroline Ferraz Rezende, Felipe Gama e Colombo, Katrini Guidolini Martinelli   +3 more
doaj   +1 more source

Membrane Wrapping for High Capacity and Rapidly Switchable Adhesives

Advanced Functional Materials, EarlyView.
A membrane‐wrapping mechanism enables high‐capacity, rapidly switchable adhesion by coupling suction, friction, and adhesion. Broadband performance is achieved in dry and underwater conditions, allowing fast, reversible manipulation of objects of diverse sizes and shapes, from delicate eggs and berries to flat, complex, or heavy objects. These outcomes
Yeunhee Kim, Camryn A. Mills, Michael D. Bartlett   +2 more
wiley   +1 more source

MAGTWIST: A Magnetically‐Driven Rotary Actuator Using a Traveling‐Wave With Integrated Stiffness Tunability

Advanced Functional Materials, EarlyView.
MAGTWIST: A compact magnetic rotary actuator, enabling smooth, stepless rotation, and on‐demand locking. Inspired by peristalsis, a soft polymer belt generates a traveling‐wave, enabling 270° rotation when heated. Cooling stiffens the belt, locking it in position and enabling it to withstand high loads.
Simon Frieler, Jean‐Paul P.M. de Vries, Sarthak Misra, Venkatasubramanian Kalpathy Venkiteswaran   +3 more
wiley   +1 more source

The effectiveness of maternal voice in critically ill children undergoing suctioning with acute pain

Jurnal Ners dan Kebidanan Indonesia, 2023
Background: Acute pain during suction in pediatric patients in the intensive care unit is unavoidable. However, it is necessary to provide non-pharmacological interventions that nurses can guide.
Astuti Astuti, Nani Nurhaeni, Fajar Tri Waluyanti, Efa Apriyanti, Juanda Mutifa, Ni Bodro Ardi   +5 more
doaj   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Wind tunnel flow generation section [PDF]

, 1974
A flow generation section for a wind tunnel test facility is described which provides a uniform flow for the wind tunnel test section over a range of different flow velocities. The throat of the flow generation section includes a pair of opposed boundary
Sorensen, N. E.
core   +1 more source

Determining the unsaturated hydraulic conductivity of a compacted sand-bentonite mixture under constant volume and free-swell conditions [PDF]

, 2008
Highly compacted sand-bentonite mixtures are often considered as possible engineered barriers in deep high-level radioactive waste disposals. In-situ, the saturation of these barriers from their initially unsaturated state is a complex hydro-mechanical ...
A.M. Tang, Blatz, Börgesson, C. Loiseau, Chiu, Cho, Cui, Daniel, Dixon, Dixon, Dixon, Haug, Hoffmann, Kenney, Komine, Kröhn, Kröhn, Lemaire, Lloret, Loiseau, Martino, P. Delage, Pusch, Villar, Y.J. Cui, Yong, Zou   +26 more
core   +4 more sources

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source