Results 31 to 40 of about 70,951 (265)

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Diagnostic predictive values of the Hain genotype MTBDRsl assay in mycobacterial strains isolated from Sudan

The Pan African Medical Journal, 2019
INTRODUCTION: Hain GenoType MTBDRsl is nucleic acid amplification assay based on reverse hybridization with specific oligonucleotide probes on nitrocellulose strips. MTBDRsl identifies M.
Muatsim Ahmed Mohammed Adam, Hamdan Mustafa Hamdan Ali, Eltahir Awad Gasim Khalil   +2 more
doaj   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Comparing the participation of men and women in academic medicine in medical colleges in Sudan: A cross-sectional survey

Journal of Education and Health Promotion, 2019
INTRODUCTION: In different countries around the world, the involvement of women in academic medicine was less in comparison with men. This study aimed to assess whether there were significant gender differences in research perception, practice, and ...
Anas Ibn Auf, Heitham Awadalla, Magda Elhadi Ahmed, Mohamed H Ahmed   +3 more
doaj   +1 more source

Multidimensional Poverty in Sudan and South Sudan [PDF]

SSRN Electronic Journal, 2015
This paper assesses multidimensional poverty in Sudan and South Sudan. We use the National Baseline Household Surveys (NBHS) of 2009 to measure poverty incidence in education, consumption, access to public assets and possession of private assets across these two countries.
Ballon, P, Duclos, J
openaire   +2 more sources

Livestock Tango: U.S. and Latin America Dance Together, but Who Will Lead?

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study examines the competitiveness between Latin American and U.S. livestock and meat sectors. We employ a computable general equilibrium modeling framework to evaluate two scenarios: coordinated improvements in Latin American productivity, transport efficiency, and market access (Scenario I), and the minimum productivity gains required ...
Taís C. Menezes, Amanda M. Countryman, Dustin L. Pendell   +2 more
wiley   +1 more source

Association of ABO blood group with plasmodium falciparum malaria in Sudanese population [PDF]

Journal of Research in Applied and Basic Medical Sciences
Background & Aims: Malaria is a febrile illness with an incubation period of one week or more. Plasmodium falciparum is responsible for the most severe forms.
Abdalla Mohamed, Mohammed Abdelmotalab, Mohamed Elbasheir   +2 more
doaj  

Temperature and Farm Labor in Nigeria

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT We estimate the impact of temperature shocks on the composition of farm labor in rural Nigeria using a nationally representative household panel survey. Leveraging plausibly exogenous year‐to‐year variation in growing season temperatures, we find that warmer temperatures significantly alter farm labor composition, prompting a substantial shift
Andu Berha
wiley   +1 more source

Navigating the crossroads: Challenges and opportunities for governance reform in Sudan

International Review of Social Sciences Research
There is a critical need for comprehensive governance reform in Sudan, a nation navigating the turbulent shift from decades of authoritarian rule to a fragile post-conflict democracy.
Fawzi Ahmed Abdullah Slom
doaj   +1 more source