Results 141 to 150 of about 83,574 (295)

Anaesthesia and Intensive Care [PDF]

open access: yes, 2004
The anaesthetist has seen his role steadily expand and it is hard to think of one medical specialty in which anaesthetists are not involved at least to some extent.
Aquilina, Andrew, Sciberras, Stephen C.
core  

The first case of Reel Syndrome in a dog after pacemaker implantation: A case report

open access: yesAustralian Veterinary Journal, EarlyView.
Reel Syndrome is a rare complication of permanent pacemaker implantation, characterised by the rotation of the device around its transverse axis, which causes the lead to coil around the generator and displacement, leading to pacing dysfunction. This report presents the first documented case of Reel Syndrome in a dog.
Z Wojtczak   +5 more
wiley   +1 more source

Improving Emergency Response in the Outpatient Clinic Setting [PDF]

open access: yes, 2015
Background: Effective triage, assessment, and activation of necessary systems in emergent situations of clinical instability is vital in reducing morbidity and mortality of patients in any clinical setting.
Horton, Matte
core   +1 more source

Sustainability in Healthcare: The Role of Digital Technologies for Improving Patient Engagement

open access: yesBusiness Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Sustainability in healthcare is getting considerable research attention as systems worldwide tend to balance environmental, social, and economic factors. In this context, digital technologies have demonstrated significant potential to enhance engagement among different consumer groups across various industries.
Francesco Schiavone   +4 more
wiley   +1 more source

Daratumumab plus bortezomib and dexamethasone (Dara‐VD) in newly diagnosed Mayo 2004 stage IIIA and IIIB light‐chain amyloidosis: Long‐term follow‐up results from a prospective phase 2 study

open access: yesBritish Journal of Haematology, EarlyView.
Summary Anti‐CD38 monoclonal antibodies dramatically improve the prognosis in immunoglobulin light‐chain (AL) amyloidosis, yet patients with end‐stage (Mayo 2004 IIIB) disease are typically excluded from prospective trials. To evaluate the daratumumab plus bortezomib and dexamethasone (Dara‐VD) regimen in Mayo 2004 stage III patients, we conducted a ...
Gao Xue‐min   +7 more
wiley   +1 more source

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi   +29 more
wiley   +1 more source

Mechanism of Cardiac Arrest in Fatal Anaphylaxis

open access: yesClinical &Experimental Allergy, EarlyView.
This population‐based retrospective cohort study of clinical deterioration in anaphylaxis deaths identifies bronchospasm as the preponderant cause of cardiac arrest, especially in food and drug allergen exposures. The clinical implication is that anaphylaxis guidelines require appropriate emphasis on respiratory involvement and treatment to prevent ...
Ben A. McKenzie   +5 more
wiley   +1 more source

A 6-year experience of CPR outcomes in an emergency department in Thailand

open access: yesTherapeutics and Clinical Risk Management, 2013
Yuwares Sittichanbuncha,1 Thidathit Prachanukool,1 Kittisak Sawanyawisuth2,31Emergency Medicine Department, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Department of Medicine, Faculty of Medicine, Khon Kaen ...
Sittichanbuncha Y   +2 more
doaj  

Love and the Basis of Dignity

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract It is often said that dignity is the ground of human rights. But what grounds dignity? According to proponents of the metaphysical view, dignity is grounded in our rational capacities, our sense of justice, or a disjunctive list of valuable capacities.
Jordan David Thomas Walters
wiley   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

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