Results 71 to 80 of about 40,890 (262)

In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments

open access: yesAdvanced Science, EarlyView.
Here, an open microfluidic platform termed “µ‐Blood” is reported for real‐time, continuous monitoring of Babesia microti infection dynamics in vitro. µ‐Blood allows direct interrogation of whole blood with preserved integrity of the original whole blood microenvironment through an extended period (e.g., 72 h with mouse red blood cells) ex vivo. µ‐Blood
Chao Li   +4 more
wiley   +1 more source

Fast Li₂O₂ Electrochemistry Enabled by Co‐Nx/Co (111) with Optimized Intermediate Adsorption

open access: yesAdvanced Science, EarlyView.
A Co‐Nx/Co (111) catalytic center demonstrates superior potential in optimizing the adsorption of desirable intermediates via regulating the electronic distribution in the cathode, thus facilitating fast redox kinetics and high rate capability, and stabilized cycling performance for aprotic Li‐O2 batteries.
Lili Liu   +7 more
wiley   +1 more source

Decreased RYR2 Cluster Size and Abnormal SR Ca2+ Release Contribute to Arrhythmogenesis in TMEM43‐Related ARVC

open access: yesAdvanced Science, EarlyView.
The TMEM43 ‐ P386S mutation causes arrhythmogenic right ventricular cardiomyopathy (ARVC) by mislocalizing itself from nuclear envelope (NE) to cytoplasm, disrupting lamin B2 (a novel TMEM43 interactor) localization, NE integrity and chromatin accessibility, causing hyper ‐ phosphorylation and reduced expression/clustering of ryanodine receptor type 2 (
Jiaxi Shen   +23 more
wiley   +1 more source

Maturation of human induced pluripotent stem cell-derived cardiomyocytes promoted by Brachyury priming

open access: yesScientific Reports
Cardiac differentiation of human induced pluripotent stem cells is readily achievable, yet derivation of mature cardiomyocytes has been a recognized limitation.
Parisa K. Kargaran   +8 more
doaj   +1 more source

Retinitis Pigmentosa‐Associated Gene TRIM49 Regulates ULK1‐Mediated Autophagy and Photoreceptor Phagocytosis by the Retinal Pigment Epithelium

open access: yesAdvanced Science, EarlyView.
Based on next‐generation sequencing data of retinitis pigmentosa (RP) patients and controls, this study identifies TRIM49 as a novel gene for autosomal recessive RP. TRIM49 is specifically expressed in the retinal pigment epithelium (RPE) of human retina.
Zhen Yi   +17 more
wiley   +1 more source

Neurochemical Alterations in Sudden Unexplained Perinatal Deaths—A Review

open access: yesFrontiers in Pediatrics, 2018
Sudden unexpected perinatal collapse is a major trauma for the parents of victims. Sudden infant death syndrome (SIDS) is unexpected and mysterious death of an apparently healthy neonate from birth till 1 year of age without any known causes, even after ...
Nazeer Muhammad   +11 more
doaj   +1 more source

Toward Practical Li‐Ion Cells With Li/Mn‐Rich Layered Oxide Cathodes: A Techno‐Economic Perspective on Material and Cell Design

open access: yesAdvanced Science, EarlyView.
 Li/Mn‐rich layered oxide cathodes should be designed systematically according to their phase diagram. Starting from a common composition (point 1), the Li‐richness can be reduced (point 2), the Co content can be lowered (point 3), and finally, the Ni to Co ratio can be adjusted.
Anindityo Arifiadi   +7 more
wiley   +1 more source

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