Results 111 to 120 of about 7,553 (218)

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, Volume 67, Issue 6, Page 3226-3242, June 2026.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

The Rhythmic and the Metronomic: On Charlie Chaplin's Gait

Critical Quarterly, EarlyView.
Matthew Beaumont
wiley   +1 more source

Patterns of seizure frequency reduction in clinical trial participants with lower baseline seizure frequency

Epilepsia, Volume 67, Issue 6, Page 2808-2819, June 2026.
Abstract Objective Inclusion and exclusion criteria of clinical trials for seizures aim to select representative participants with a high enough seizure frequency to evaluate the efficacy of treatment in a relatively short double‐blind period. To inform the selection of seizure frequency‐based inclusion criteria, we evaluated the association between ...
Wesley T. Kerr, Advith S. Reddy, Neo Kok, Katherine N. McFarlane, Lavanya Biju, Jacqueline A. French   +5 more
wiley   +1 more source

Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain

Epilepsia, Volume 67, Issue 6, Page 3171-3184, June 2026.
Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley   +1 more source

Sudden cardiac death (SCD) and sudden unexpected death in epilepsy (SUDEP)

, 2019
Sudden unexpected death in people previously considered healthy represents an important challenge for modern medicine. The causes of this phenomenon are constantly being sought and attempts are being made to understand its pathomechanism.
Mańka-Gaca, Iwona, Łabuz-Roszak, Beata
core  

Sudden unexpected death in epilepsy: Measures to reduce risk

, 2017
This review looks at the strategies that may help to reduce the risk of sudden unexpected death in epilepsy beyond that of trying to achieve seizure cessation, which is not possible for up to 30% of patients with epilepsy.
Jory, C, Shankar, Rohit, Newman, Craig, Shankar, R, Newman, C, Hanna, Jane, McLean, Brendan, Jory, Caryn, Mclean, B, Hanna, J   +9 more
core   +1 more source

Does having bad epilepsy make you a good surgical candidate? A number needed to treat analysis

Epilepsia Open, Volume 11, Issue 3, Page 692-701, June 2026.
Abstract Epilepsy surgery is an established treatment for drug‐resistant epilepsy, offering a realistic prospect of seizure freedom in well‐selected candidates. However, surgery is sometimes offered to individuals with a low probability of seizure freedom when it is framed as potentially “life‐saving” on the basis of the elevated mortality associated ...
Sallie Baxendale, Dominic Heaney, Matthew C. Walker   +2 more
wiley   +1 more source

Subclinical hyperthyroidism and sudden unexpected death in epilepsy

, 2010
Epilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death.
Albuquerque, Manly de [UNIFESP], ALBUQUERQUE, Manly de, CYSNEIROS, Roberta M., Scorza, Fulvio A. [UNIFESP], TERRA, Vera C., CAVALHEIRO, Esper A., Arida, Ricardo M. [UNIFESP], MACHADO, Helio R., Cavalheiro, Esper A. [UNIFESP], SCORZA, Fulvio A., ARIDA, Ricardo M.   +10 more
core   +1 more source

The Global Epilepsy Needs Study (GENS): A mixed‐methods, multi‐country exploration of the unmet psychosocial and everyday needs of people with epilepsy

Epilepsia Open, Volume 11, Issue 3, Page 814-832, June 2026.
Abstract Objective While epilepsy research has largely focused on medical management and clinical outcomes, less attention has been given to the unmet psychosocial and everyday needs of people with epilepsy (PWE), particularly in low‐ and middle‐income countries.
Gus A. Baker, Sandeep Kumar Bagga, Donna Walsh, Claire Nolan, Shivani Sharma, Charlotte Hooker, Pepa Gonzalez Parrao, Francesca Sofia, J. Helen Cross, Ma. Marta Bertone, Ivana García, Adam Jallow Janneh, Alison Kukla, Elvira Vacas Montero, Ding Ding, Latica Friedrich, Lecio Figueira Pinto, Gagandeep Singh, Chahnez Charfi Triki, Leya Raj, Allan Reese, on behalf of GENS Collaborators, Naziya Anzari, Alicia Bogacz, Martin Brodie, Heather Brooks, Nicole Coulthard, Laura Dickson, Laura Maria de Figueiredo Ferreira Guilhoto, Anchor Hung, John Nute Jabang, Boram Lee, Kheng‐Seang Lim, Rebecca Lisle, Anita Mago, Sharon Mbugua, Bindu Menon, Sarah Nekesa, Youssouf Noormamode, Per Olesen, Kris Pierce, Dzenana Rustempasic, Jitendra K. Sahu, Ana Sruk, Christa Studzinski, Nirmal Surya, Maria Alice Susemihl, Laura Weidner, Samuel Wiebe, Andrea Wilkinson, Leonie Wollscheid, Ian Wong, Bernadette Zappa   +52 more
wiley   +1 more source

Epilepsia partialis continua as the presenting manifestation of Creutzfeldt–Jakob disease: A video‐polygraphic clinical vignette

Epileptic Disorders, Volume 28, Issue 3, Page 920-924, June 2026.
Roberta Cutellè, Angelo Pascarella, Ada Santoro, Vittoria Cianci, Anna Mammì, Giovanbattista Gaspare Tripodi, Caterina Prestandrea, Sara Gasparini, Edoardo Ferlazzo   +8 more
wiley   +1 more source