Results 51 to 60 of about 3,526 (182)

Responsive stimulation of the thalamus for idiopathic generalized epilepsy: Results of the randomized controlled NAUTILUS trial through 18 months

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive therapy for drug‐resistant idiopathic generalized epilepsy (IGE) with generalized tonic–clonic seizures (GTCSs). Methods NAUTILUS is a prospective, multicenter, single‐blind, randomized sham‐controlled pivotal trial ...
Utku Uysal   +47 more
wiley   +1 more source

SUDEP in patients with epilepsy and nonepileptic seizures [PDF]

open access: yesEpilepsia Open, 2019
AbstractWe report 13 SUDEP cases in the North American SUDEP Registry with both psychogenic nonepileptic seizures (PNES) and epileptic seizures (ES) among a consecutive series of 231 cases (excluding epileptic encephalopathies). On average, cases of PNES + ES died at a younger age (23 ± 11 years) than the ES‐only cohort (30 ± 14 years), and died an ...
Chloe Verducci   +2 more
openaire   +3 more sources

Tonic–clonic seizures captured during ambulatory video‐EEG are frequently unreported

open access: yesEpilepsia, EarlyView.
Abstract Objective Tonic–clonic seizures (TCSs) are widely regarded as clinically obvious, yet seizure counts used for treatment decisions and risk counseling often rely on patient or caregiver diaries. We sought to quantify the frequency of unreported TCSs during prolonged ambulatory video‐EEG (vEEG) monitoring and examined associations with ...
Ewan S. Nurse   +3 more
wiley   +1 more source

Time of Day and a Ketogenic Diet Influence Susceptibility to SUDEP in Scn1aR1407X/+ Mice

open access: yesFrontiers in Neurology, 2019
Sudden unexpected death in epilepsy (SUDEP) is a major cause of mortality in patients with drug-resistant epilepsy. Most SUDEP cases occur in bed at night and are preceded by a generalized tonic-clonic seizure (GTCS).
Frida A. Teran   +12 more
doaj   +1 more source

How Much is SUDEP Known by Patients by Epilepsy?

open access: yesArchives of Epilepsy, 2023
Objective:Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in patients with epilepsy. The issue of informing every epilepsy patient and/or their relatives about SUDEP remains controversial. We evaluated the level of knowledge
Firdevs Ezgi Uçan Tokuç   +3 more
doaj   +1 more source

Audiogenic epileptic DBA/2 mice strain as a model of genetic reflex seizures and SUDEP

open access: yesFrontiers in Neurology, 2023
Epilepsy is a chronic neurological disease characterized by abnormal brain activity, which results in repeated spontaneous seizures. Sudden unexpected death in epilepsy (SUDEP) is the leading cause of seizure-related premature death, particularly in drug-
Francesca Bosco   +11 more
doaj   +1 more source

Compensatory rearrangement of parvalbumin interneuron voltage‐gated sodium channel subunits in a mouse model of Dravet syndrome

open access: yesEpilepsia, EarlyView.
Abstract Heterozygous loss‐of‐function variants in the gene SCN1A, which encodes the voltage‐gated sodium channel (VGSC) pore‐forming (α) subunit NaV1.1, lead to a spectrum of neurological disease, including Dravet syndrome. NaV1.1 is prominently expressed at the proximal portion of the axon initial segment (AIS) of fast‐spiking γ‐aminobutyric ...
Ania K. Dabrowski   +4 more
wiley   +1 more source

Muerte súbita en epilepsia: casuística de una unidad médica de epilepsia española

open access: yesNeurología, 2020
Resumen: Introducción: La muerte súbita en epilepsia (SUDEP) es la causa más frecuente de muerte atribuible a la propia enfermedad. Casi toda la información sobre esta entidad procede de estudios realizados en el centro/norte de Europa y Estados Unidos.
M.I. Chamorro-Muñoz   +4 more
doaj   +1 more source

Dorsal raphe nucleus to pre-Bötzinger complex serotonergic neural circuit is involved in seizure-induced respiratory arrest

open access: yesiScience, 2022
Summary: Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among patients with epilepsy. However, the underlying mechanism of SUDEP remains elusive.
HaiXiang Ma   +11 more
doaj   +1 more source

Project SUDEP-actie

open access: yesEpilepsie, periodiek voor professionals, 2021
Het Netwerk Epilepsiezorg heeft in het project SUDEP-actie twee folders ontwikkeld over SUDEP, één voor patiënten en één voor professionals. Het doel van het project is meer bewustwording creëren over SUDEP en tegelijkertijd informatie beschikbaar stellen.
openaire   +2 more sources

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