Results 201 to 210 of about 65,550 (268)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

When Standard Newborn Screening Isn't Enough: Diagnostic Challenges in the Age of Globalization. [PDF]

Clin Case Rep
Ortúzar Menéndez M, Mendiguren LM, Garde Garde MC, Pérez Ollo S, Campion Mezquiriz A, Moreno-Galarraga L.   +5 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Quantum theories of consciousness: a critical review of feasibility, philosophical sufficiency, and empirical testability. [PDF]

Front Psychol
Ma X, Wang A.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Social determinants of health and quality of life among Korean Americans with chronic hepatitis B. [PDF]

BMC Public Health
Fang CX, Nam Y, Klassen AC, Juon HS.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Serum 25-hydroxyvitamin D is associated with islet function in postmenopausal women with type 2 diabetes and osteoporosis. [PDF]

Front Endocrinol (Lausanne)
Yin X, Sun X, Gao F, Wang X, Chen P, Yang X, Guo N, Wang G, Xu J, Fu D.   +9 more
europepmc   +1 more source

Vitamin D Status and Test Utilization: A Five-Year Analysis. [PDF]

Cureus
Al Maqbali S, Al Maharbi H, Al Handhali S, Al Hashimi T, Anwar S, Alswaii T.   +5 more
europepmc   +1 more source

Augmented inventorship: rethinking patent law in the age of generative AI. [PDF]

J Law Biosci
Levy HV.
europepmc   +1 more source