Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Navigating AI feedback in translation training: how text type, proficiency, and attitude shape students' acceptance behaviors. [PDF]
Chen S, Lou J.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Enabling Auto-Correction on Soft Braille Keyboard. [PDF]
Zhang D +6 more
europepmc +1 more source
Characteristics of transferrin saturation and anemia-related biomarkers in patients with uterine adenomyosis. [PDF]
Kawamata M +7 more
europepmc +1 more source
Geomagnetic and visual cues guide seasonal migratory orientation in the nocturnal fall armyworm, the world's most invasive insect. [PDF]
Ma YB +9 more
europepmc +1 more source
"Ultrasonic elastography-guided pleural biopsy <i>versus</i> traditional thoracic ultrasound-guided pleural biopsy for the diagnosis of pleural effusion: a multicentre, randomised trial." M. Deng, Y. Xia, X. Ye, <i>et al</i>. <i>Eur Respir J</i> 2025; 66: 2501062. [PDF]
europepmc +1 more source

